Results 11 to 20 of about 268,731 (242)
Suspension-cultured taste bud organoids recapitulate in vivo taste buds [PDF]
Organoid, 2023 Background Taste buds are a complex organ and require a plethora of growth factors for their development, homeostasis, and regeneration. Taste bud organoids provide a platform for understanding their development, disease and regeneration. Methods In this
Anish Ashok Adpaikar +2 more
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β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice. [PDF]
PLoS Genetics, 2017 Taste stimuli are transduced by taste buds and transmitted to the brain via afferent gustatory fibers. Renewal of taste receptor cells from actively dividing progenitors is finely tuned to maintain taste sensitivity throughout life.
Dany Gaillard +5 more
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Rapid structural remodeling of peripheral taste neurons is independent of taste cell turnover.
PLoS Biology, 2023 Taste bud cells are constantly replaced in taste buds as old cells die and new cells migrate into the bud. The perception of taste relies on new taste bud cells integrating with existing neural circuitry, yet how these new cells connect with a taste ...
Zachary D Whiddon +4 more
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Genome-Wide Analysis of Gene Expression in Primate Taste Buds Reveals Links to Diverse Processes [PDF]
PLoS ONE, 2009 Efforts to unravel the mechanisms underlying taste sensation (gustation) have largely focused on rodents. Here we present the first comprehensive characterization of gene expression in primate taste buds.
Albert Zlotnik +2 more
exaly +2 more sources
Whole transcriptome profiling of taste bud cells [PDF]
Scientific Reports, 2017 Analysis of single-cell RNA-Seq data can provide insights into the specific functions of individual cell types that compose complex tissues. Here, we examined gene expression in two distinct subpopulations of mouse taste cells: Tas1r3-expressing type II ...
Sunil K. Sukumaran +5 more
doaj +2 more sources
Fine-tuning of epithelial taste bud organoid to promote functional recapitulation of taste reactivity. [PDF]
Cell Mol Life Sci, 2022 Taste stem/progenitor cells from posterior mouse tongues have been used to generate taste bud organoids. However, the inaccessible location of taste receptor cells is observed in conventional organoids.
Adpaikar AA +6 more
europepmc +2 more sources
Voltage-gated sodium channels in taste bud cells [PDF]
BMC Neuroscience, 2009 Background Taste bud cells transmit information regarding the contents of food from taste receptors embedded in apical microvilli to gustatory nerve fibers innervating basolateral membranes.
Williams Mark E +8 more
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Maintenance and turnover of Sox2+ adult stem cells in the gustatory epithelium.
PLoS ONE, 2022 Continuous turnover of taste bud cells in the oral cavity underlies the homeostasis of taste tissues. Previous studies have demonstrated that Sox2+ stem cells give rise to all types of epithelial cells including taste bud cells and non-gustatory ...
Makoto Ohmoto +5 more
doaj +1 more source
The umami receptor T1R1–T1R3 heterodimer is rarely formed in chickens
Scientific Reports, 2021 The characterization of molecular mechanisms underlying the taste-sensing system of chickens will add to our understanding of their feeding behaviors in poultry farming. In the mammalian taste system, the heterodimer of taste receptor type 1 members 1/3 (
Yuta Yoshida +3 more
doaj +1 more source
Applied Sciences, 2023 Taste perception plays a crucial role in health and well-being but can be compromised by conditions such as diabetes mellitus (DM). This study delved into the efficacy of 4-hexylresorcinol (4-HR) in mitigating taste bud apoptosis, particularly in ...
Dhouha Gaida +2 more
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