Results 21 to 30 of about 6,869 (288)
A taste for ATP: neurotransmission in taste buds [PDF]
Frontiers in Cellular Neuroscience, 2013 Not only is ATP a ubiquitous source of energy but it is also used widely as an intercellular signal. For example, keratinocytes release ATP in response to numerous external stimuli including pressure, heat, and chemical insult. The released ATP activates purinergic receptors on nerve fibers to generate nociceptive signals.
Kinnamon, Sue C., Finger, Thomas E.
openaire +3 more sources
Applied Sciences, 2023 Taste perception plays a crucial role in health and well-being but can be compromised by conditions such as diabetes mellitus (DM). This study delved into the efficacy of 4-hexylresorcinol (4-HR) in mitigating taste bud apoptosis, particularly in ...
Dhouha Gaida +2 more
doaj +1 more source
Development and validation of a contouring guideline for the taste bud bearing tongue mucosa. [PDF]
Radiother Oncol, 2021 PURPOSE: To introduce a contouring guideline for the taste bud bearing tongue mucosa for head and neck cancer patients receiving radiotherapy. METHODS AND MATERIALS: CT simulation images of oropharyngeal cancer patients were used to delineate both the ...
Stieb S +18 more
europepmc +2 more sources
Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling. [PDF]
PLoS Genetics, 2016 For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions.
Alexandre N Ermilov +7 more
doaj +1 more source
A2BR adenosine receptor modulates sweet taste in circumvallate taste buds. [PDF]
PLoS ONE, 2012 In response to taste stimulation, taste buds release ATP, which activates ionotropic ATP receptors (P2X2/P2X3) on taste nerves as well as metabotropic (P2Y) purinergic receptors on taste bud cells.
Shinji Kataoka +7 more
doaj +1 more source
Fingerprinting taste buds: intermediate filaments and their implication for taste bud formation [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000 Intermediate filaments in taste organs of terrestrial (human and chick) as well as aquatic (Xenopus laevis) species were detected using immunohistochemistry and electron microscopy. During development, the potential importance of the interface between the taste bud primordium and non–gustatory, adjacent tissues is evidenced by the distinct ...
M, Witt +3 more
openaire +2 more sources
Taste isn't just for taste buds anymore [PDF]
F1000 Biology Reports, 2011 Taste is a discriminative sense involving specialized receptor cells of the oral cavity (taste buds) and at least two distinct families of G protein-coupled receptor molecules that detect nutritionally important substances or potential toxins. Yet the receptor mechanisms that drive taste also are utilized by numerous systems throughout the body.
Finger, Thomas E., Kinnamon, Sue C.
openaire +2 more sources
Is fat the sixth taste primary? Evidence and implications [PDF]
, 2015 Explores our tongue\u27s ability to detect fat as a distinct taste similar to our ability to sense sweet, sour, bitter, acid and savory. Abstract Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For
Russell Keast +2 more
core +1 more source
Functional cell types in taste buds have distinct longevities. [PDF]
PLoS ONE, 2013 Taste buds are clusters of polarized sensory cells embedded in stratified oral epithelium. In adult mammals, taste buds turn over continuously and are replenished through the birth of new cells in the basal layer of the surrounding non-sensory epithelium.
Isabel Perea-Martinez +2 more
doaj +1 more source
Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds. [PDF]
PLoS ONE, 2016 Growth factors regulate cell growth and differentiation in many tissues. In the taste system, as yet unknown growth factors are produced by neurons to maintain taste buds.
Bradley T Biggs, Tao Tang, Robin F Krimm
doaj +1 more source