Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source
The non-synthetic sweeteners, miraculin and mogroside V, but not stevia, disrupt the intestinal epithelial barrier function through a sweet taste receptor-dependent mechanism. [PDF]
Shil A, Amoakohene O, Chichger H.
europepmc +1 more source
Associations of Sleep and Shift Work with Osteoarthritis Risk
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik +5 more
wiley +1 more source
High-fat diet-induced anorexia in rats: involving orosensory deficits, gastrointestinal dysfunction, intestinal taste receptor downregulation and dopamine signaling dysregulation. [PDF]
Ye Q +6 more
europepmc +1 more source
Dynamic Precipitation during High‐Pressure Torsion of a Magnesium–Manganese Alloy
An ultrafine‐grained alloy is produced by high‐pressure torsion of solutionized Mg–1.35 wt% Mn. Precipitation of nanometer‐scale Mn particles during deformation provides pinning sites. This prevents the formation of a bimodal grain structure and results in a finer grain size than for pure Mg.
Julian M. Rosalie, Anton Hohenwarter
wiley +1 more source
The three-dimensional structure prediction of human bitter taste receptor using the method of AlphaFold3. [PDF]
Shimizu T +7 more
europepmc +1 more source
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti +5 more
wiley +1 more source
Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs. [PDF]
Óvilo C +9 more
europepmc +1 more source
Bitter taste receptor (TAS2R) 46 in human skeletal muscle: expression and activity. [PDF]
Talmon M +13 more
europepmc +1 more source
The functional role of the T1R family of receptors in sweet taste and feeding
Yada Treesukosol +2 more
openalex +2 more sources

