Results 21 to 30 of about 2,584,981 (353)

The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis

ImmunoHorizons, 2020
Tuft cells are an epithelial cell type critical for initiating type 2 immune responses to parasites and protozoa in the small intestine. To respond to these stimuli, intestinal tuft cells use taste chemosensory signaling pathways, but the role of taste ...
Michael R. Howitt, Y. G. Cao, Matthew B Gologorsky, Jessica A Li, Adam L. Haber, Moshe Biton, Jessica K. Lang, M. Michaud, A. Regev, W. Garrett   +9 more
semanticscholar   +1 more source

Comparing the difference in enhancement of kokumi-tasting γ-glutamyl peptides on basic taste via molecular modeling approaches and sensory evaluation

Food Science and Human Wellness, 2022
γ-Glutamyl peptides can enhance basic taste sensations such as saltiness, sweetness, and umaminess, while the molecular mechanism and the difference in taste enhancement remain elusive.
Juan Yang, Jing Guo, Ruijie Mai, Hao Dong, Chun Cui, Xiaofang Zeng, Weidong Bai   +6 more
doaj   +1 more source

Expression of Taste Receptor 2 Subtypes in Human Testis and Sperm

Journal of Clinical Medicine, 2020
Taste receptors (TASRs) are expressed not only in the oral cavity but also throughout the body, thus suggesting that they may play different roles in organ systems beyond the tongue.
L. Governini, Bianca Semplici, V. Pavone, Laura Crifasi, Camilla Marrocco, V. de Leo, Elisabeth Arlt, T. Gudermann, I. Boekhoff, A. Luddi, P. Piomboni   +10 more
semanticscholar   +1 more source

Bitter taste receptors [PDF]

Evolution, Medicine, and Public Health, 2021
AbstractBitter taste perception plays vital roles in animal behavior and fitness. By signaling the presence of toxins in foods, particularly noxious defense compounds found in plants, it enables animals to avoid exposure. In vertebrates, bitter perception is initiated by TAS2Rs, a family of G protein-coupled receptors expressed on the surface of taste ...
Stephen P Wooding, Vicente A Ramirez, Maik Behrens   +2 more
openaire   +3 more sources

Genetics of Taste Receptors [PDF]

Current Pharmaceutical Design, 2014
Taste receptors function as one of the interfaces between internal and external milieus. Taste receptors for sweet and umami (T1R [taste receptor, type 1]), bitter (T2R [taste receptor, type 2]), and salty (ENaC [epithelial sodium channel]) have been discovered in the recent years, but transduction mechanisms of sour taste and ENaC-independent salt ...
Alexander A, Bachmanov, Natalia P, Bosak, Cailu, Lin, Ichiro, Matsumoto, Makoto, Ohmoto, Danielle R, Reed, Theodore M, Nelson   +6 more
openaire   +2 more sources

A2BR adenosine receptor modulates sweet taste in circumvallate taste buds. [PDF]

PLoS ONE, 2012
In response to taste stimulation, taste buds release ATP, which activates ionotropic ATP receptors (P2X2/P2X3) on taste nerves as well as metabotropic (P2Y) purinergic receptors on taste bud cells.
Shinji Kataoka, Arian Baquero, Dan Yang, Nicole Shultz, Aurelie Vandenbeuch, Katya Ravid, Sue C Kinnamon, Thomas E Finger   +7 more
doaj   +1 more source

Photostimulation of Ventral Tegmental Area-Insular Cortex Dopaminergic Inputs Enhances the Salience to Consolidate Aversive Taste Recognition Memory via D1-Like Receptors

Frontiers in Cellular Neuroscience, 2022
Taste memory involves storing information through plasticity changes in the neural network of taste, including the insular cortex (IC) and ventral tegmental area (VTA), a critical provider of dopamine.
Elvi Gil-Lievana, Gerardo Ramírez-Mejía, Oscar Urrego-Morales, Jorge Luis-Islas, Ranier Gutierrez, Federico Bermúdez-Rattoni   +5 more
doaj   +1 more source

Does ENaC Work as Sodium Taste Receptor in Humans?

Nutrients, 2020
Taste reception is fundamental for the proper selection of food and beverages. Among the several chemicals recognized by the human taste system, sodium ions (Na+) are of particular relevance.
A. Bigiani
semanticscholar   +1 more source

Mammalian Sweet Taste Receptors [PDF]

Cell, 2001
The sense of taste provides animals with valuable information about the quality and nutritional value of food. Previously, we identified a large family of mammalian taste receptors involved in bitter taste perception (the T2Rs). We now report the characterization of mammalian sweet taste receptors.
Nelson, Greg, Hoon, Mark A., Chandrashekar, Jayaram, Zhang, Yifeng, Ryba, Nicholas J.P., Zuker, Charles S.   +5 more
openaire   +2 more sources

Characterization of the Sweet Taste Receptor Tas1r2 from an Old World Monkey Species Rhesus Monkey and Species-Dependent Activation of the Monomeric Receptor by an Intense Sweetener Perillartine. [PDF]

PLoS ONE, 2016
Sweet state is a basic physiological sensation of humans and other mammals which is mediated by the broadly acting sweet taste receptor-the heterodimer of Tas1r2 (taste receptor type 1 member 2) and Tas1r3 (taste receptor type 1 member 3).
Chenggu Cai, Hua Jiang, Lei Li, Tianming Liu, Xuejie Song, Bo Liu   +5 more
doaj   +1 more source