Results 41 to 50 of about 2,584,981 (353)
TAS2R38 bitter taste receptor and attainment of exceptional longevity
Scientific Reports, 2019 Bitter taste receptors play crucial roles in detecting bitter compounds not only in the oral cavity, but also in extraoral tissues where they are involved in a variety of non‒tasting physiological processes.
Melania Melis +4 more
semanticscholar +1 more source
Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes
Frontiers in Immunology, 2018 The human G-protein-coupled bitter taste receptor T2R38 has recently been demonstrated to be expressed on peripheral blood neutrophils, monocytes and lymphocytes.
H. Tran +4 more
semanticscholar +1 more source
Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice
Scientific Reports, 2017 Asthma is characterized by airway inflammation, mucus secretion, remodeling and hyperresponsiveness (AHR). Recent research has established the bronchodilatory effect of bitter taste receptor (TAS2R) agonists in various models.
Pawan Sharma +8 more
semanticscholar +1 more source
Progress on the Tasting Mechanism and Computer Aided Analysis of Food Taste-Modulating Peptides
Shipin gongye ke-jiFood taste-modulating peptides mainly interact with salt taste receptor ENaC, TRPV1 or TMC4, umami receptor T1R1/T1R3, sweet receptor T1R2/T1R3, bitter receptor T2R and kokumi receptor CaSR to induce PLCβ2/IP3 or cAMP/PKA pathway to achieve taste ...
Dongting YANG +4 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Taste receptors exist in several organs from tongue to colon and have diverse functions dependent on specific cell type. In enteroendocrine L-cells, stimulation of taste receptor signaling induces incretin hormones. Among incretin hormones, glucagon-like
Kang-Hoon Kim +5 more
semanticscholar +1 more source
A sweet taste receptor‐dependent mechanism of glucosensing in hypothalamic tanycytes
Glia, 2017 Hypothalamic tanycytes are glial‐like glucosensitive cells that contact the cerebrospinal fluid of the third ventricle, and send processes into the hypothalamic nuclei that control food intake and body weight.
Heather Benford +8 more
semanticscholar +1 more source
Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. [PDF]
PLoS ONE, 2009 BACKGROUND:Sweet taste receptor is expressed in the taste buds and enteroendocrine cells acting as a sugar sensor. We investigated the expression and function of the sweet taste receptor in MIN6 cells and mouse islets.
Yuko Nakagawa +9 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2018 Bitter (T2R) and sweet taste (T1R) receptors have emerged as regulators of upper airway immune responses. Genetic variation of these taste receptors additionally confers susceptibility to infection and has been implicated in severity of disease in ...
Vasiliki Triantafillou +4 more
doaj +1 more source
Diet-induced obesity reduces the responsiveness of the peripheral taste receptor cells. [PDF]
PLoS ONE, 2013 INTRODUCTION: Obesity is a growing epidemic that causes many serious health related complications. While the causes of obesity are complex, there is conclusive evidence that overconsumption coupled with a sedentary lifestyle is the primary cause of this ...
Amanda B Maliphol +2 more
doaj +1 more source
Sweet Taste Is Complex: Signaling Cascades and Circuits Involved in Sweet Sensation
Frontiers in Human Neuroscience, 2021 Sweetness is the preferred taste of humans and many animals, likely because sugars are a primary source of energy. In many mammals, sweet compounds are sensed in the tongue by the gustatory organ, the taste buds.
Elena von Molitor +6 more
doaj +1 more source