Results 21 to 30 of about 854,024 (332)

Measurement of the $\tau$ lepton polarization and $R(D^*)$ in the decay $\bar{B} \rightarrow D^* \tau^- \bar{\nu}_\tau$ with one-prong hadronic $\tau$ decays at Belle [PDF]

open access: yes, 2017
With the full data sample of $772 \times 10^6$ $B{\bar B}$ pairs recorded by the Belle detector at the KEKB electron-positron collider, the decay $\bar{B} \rightarrow D^* \tau^- \bar{\nu}_\tau$ is studied with the hadronic $\tau$ decays $\tau ...
Adachi, I.   +185 more
core   +3 more sources

Adenosine A2A receptor binding profile of two antagonists, ST1535 and KW6002: consideration on the presence of atypical adenosine A2A binding sites

open access: yesFrontiers in Psychiatry, 2010
Adenosine A2A receptors seem to exist in typical (more in striatum) and atypical (more in hippocampus and cortex) subtypes. In the present study, we investigated the affinity of two adenosine A2A receptor antagonists, ST1535 [2 butyl -9-methyl-8-(2H-1,2 ...
Teresa Riccioni   +2 more
doaj   +1 more source

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

open access: yesNature Communications, 2020
The αvβ6 integrin is key in activating the pro-fibrotic cytokine TGFβ in idiopathic pulmonary fibrosis. Here, the authors show an inhaled small molecule αvβ6 inhibitor GSK3008348 induces prolonged inhibition of TGFβ signaling pathways in human and murine
Alison E. John   +36 more
doaj   +1 more source

Tau here, tau there, tau almost everywhere: Clarifying the distribution of tau in the adult CNS

open access: yesCytoskeleton, 2023
AbstractThe microtubule‐associated protein tau has gained significant attention over the last several decades primarily due to its apparent role in the pathogenesis of several diseases, most notably Alzheimer's disease. While the field has focused largely on tau's potential contributions to disease mechanisms, comparably less work has focused on normal
openaire   +2 more sources

Tau Pathology Generated by Overexpression of Tau [PDF]

open access: yesThe American Journal of Pathology, 1999
Neurofibrillary changes of abnormally hyperphosphorylated tau are the key lesion in Alzheimer’s disease (AD) and a number of other tauopathies. Recent developments in the field of autosomal dominantly inherited dementias, in particular the frontotemporal dementias and Parkinsonism linked to chromosome 17 (FTDP-17) group, have shown that abnormalities ...
Khalid Iqbal, Inge Grundke-Iqbal
openaire   +3 more sources

A Co-Operative Autonomous Offshore System for Target Detection Using Multi-Sensor Technology

open access: yesRemote Sensing, 2020
This article studies the design, modeling, and implementation challenges for a target detection algorithm using multi-sensor technology of a co-operative autonomous offshore system, formed by an unmanned surface vehicle (USV) and an autonomous underwater
Jose Villa   +3 more
doaj   +1 more source

The tau code [PDF]

open access: yesFrontiers in Aging Neuroscience, 2009
In this short review, I will focus on how a unique tau gene may produce many tau isoforms through alternative splicing and how the phosphorylation of these isoforms by different kinases may affect their activity and behaviour. Indeed, each of the different tau isoforms may play a distinct role under both physiological and pathological conditions. Thus,
openaire   +4 more sources

The initial stage of the development of the semi-free population of the Przewalski's horse in the Orenburg State Nature Reserve (Russia)

open access: yesNature Conservation Research: Заповедная наука, 2019
The Joint Directorate of the State Nature Reserves «Orenburg» and «Shaitan-Tau» (later – FSFI «Orenburg Reserves») elaborated the Programme on establishing a semi-free population of the Przewalski's horse in the Orenburg State Nature Reserve (Russia). It
Rafilia T. Bakirova   +2 more
doaj   +1 more source

Model-Validation and Implementation of a Path-Following Algorithm in an Autonomous Underwater Vehicle

open access: yesApplied Sciences, 2021
This article studies the design, modeling, and implementation of a path-following algorithm as a guidance, navigation, and control (GNC) architecture for an autonomous underwater vehicle (AUV).
Jose Villa   +4 more
doaj   +1 more source

Fabrication of self-supporting structures made of washcoat materials (γ-Al2O3-CeO2) by ceramic stereolithography: Towards digital manufacturing of enhanced catalytic converters

open access: yesMaterials & Design, 2021
Despite increasing interest in the use of alternative fuel, conventional diesel or gasoline powered vehicles still dominate road transportation; removal of their emitted pollutants is a challenge to sustainable transportation. The automotive industry has
Setareh Zakeri   +5 more
doaj  

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