Results 131 to 140 of about 5,909,902 (374)

Biodegradable and Recyclable Luminescent Mixed‐Matrix‐Membranes, Hydrogels, and Cryogels based on Nanoscale Metal‐Organic Frameworks and Biopolymers

Advanced Functional Materials, EarlyView.
The study presents biodegradable and recyclable mixed‐matrix membranes (MMMs), hydrogels, and cryogels using luminescent nanoscale metal‐organic frameworks (nMOFs) and biopolymers. These bio‐nMOF‐MMMs combine europium‐based nMOFs as probes for the status of the materials with the biopolymers agar and gelatine and present alternatives to conventional ...
Moritz Maxeiner, Julian Burkhart, Kateryna Borysova, Chiara Mazzariol, Klaus Müller‐Buschbaum   +4 more
wiley   +1 more source

Parallel implementation of stochastic simulation for large-scale cellular processes [PDF]

, 2005
Experimental and theoretical studies have shown the importance of stochastic processes in genetic regulatory networks and cellular processes. Cellular networks and genetic circuits often involve small numbers of key proteins such as transcriptional ...
Burrage, K., Tian, T.
core   +2 more sources

Corrigendum: Synthetic torpor triggers a regulated mechanism in the rat brain, favoring the reversibility of Tau protein hyperphosphorylation [PDF]

, 2023
Fabio Squarcio, Timna Hitrec, Emiliana Piscitiello, Matteo Cerri, Catia Giovannini, Davide Martelli, Alessandra Occhinegro, Ludovico Taddei, Domenico Tupone, Roberto Amici, Marco Luppi   +10 more
openalex   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

Advanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

Sensitivity analysis of a mathematical model of Alzheimer's disease progression unveils important causal pathways

Frontiers in Neuroinformatics
IntroductionMathematical models serve as essential tools to investigate brain aging, the onset of Alzheimer's disease (AD) and its progression. By studying the representation of the complex dynamics of brain aging processes, such as amyloid beta (Aβ ...
Seyedadel Moravveji, Halima Sadia, Halima Sadia, Nicolas Doyon, Nicolas Doyon, Simon Duchesne, Simon Duchesne, Simon Duchesne   +7 more
doaj   +1 more source

Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH. [PDF]

, 2019
Tau, a member of the MAP2/tau family of microtubule-associated proteins, stabilizes and organizes axonal microtubules in healthy neurons. In neurodegenerative tauopathies, tau dissociates from microtubules and forms neurotoxic extracellular aggregates ...
Barber, Diane L, Charafeddine, Rabab A, Cortopassi, Wilian A, Jacobson, Matthew P, Lak, Parnian, McKenney, Richard J, Tan, Ruensern, Wittmann, Torsten   +7 more
core  

Neuroprotection targeting protein misfolding on chronic cerebral hypoperfusion in the context of metabolic syndrome [PDF]

, 2018
Metabolic syndrome (MetS) is a cluster of risk factors that lead to microvascular dysfunction and chronic cerebral hypoperfusion (CCH). Long-standing reduction in oxygen and energy supply leads to brain hypoxia and protein misfolding, thereby linking CCH
Capani, Francisco, Herrera, María Inés, Kusnier, Carlos Federico, Luaces, Juan Pablo, Otero-Losada, Matilde Estela, Toro Urrego, Nicolás, Udovin, Lucas   +6 more
core   +1 more source

Multifunctional Protein Eutectogels Based on Polyphenolic: Zwitterionic Low‐Transition‐Temperature Mixtures

Advanced Functional Materials, EarlyView.
This work presents the first example of multifunctional protein eutectogels based on a tannic acid: betaine low‐transition‐temperature mixture, exhibiting elastomeric behavior, strong adhesion to various substrates, including biological tissues, and notable anti‐inflammatory properties derived from the natural polyphenol and zwitterion.
Sergio Martin‐Saldaña, Alberto de León, María de la Mata, Nikolaos Politakos, Jorge L. Olmedo‐Martínez, Alejandro J. Müller, Ana Beloqui, Marcelo Calderón, Matias L. Picchio   +8 more
wiley   +1 more source

Dissociation of Clinical Outcomes and CSF Proteinopathy Biomarkers in Parkinson’s Disease: Cognitive–Affective Dissociation with Specificity for Tau

Biomedicines
Background: Parkinson’s disease (PD) is characterized not only by motor dysfunction but also by widespread degeneration across cortico-striatal, limbic, and cortical circuits.
João Paulo Mota Telles, Lucas Camargo, Anna Carolyna Gianlorenço, Felipe Fregni   +3 more
doaj   +1 more source

Transport by molecular motors in the presence of static defects [PDF]

, 2009
The transport by molecular motors along cytoskeletal filaments is studied theoretically in the presence of static defects. The movements of single motors are described as biased random walks along the filament as well as binding to and unbinding from the
A. Ebneth, A. Parmeggiani, A. Seitz, A. Seitz, A.B. Kolomeisky, B. Schmittmann, B.M. Paschal, C. Leduc, E.-M. Mandelkow, G. Tripathy, G.A. Klein, G.M. Schütz, H. Hagiwara, H. Hess, I.M. Crevel, J. Beeg, J. Howard, J. Krug, J.-C. Larcher, J.C. Bulisnki, K. Nishinari, K. Tokuraku, L.A. Lopez, L.J. Davis, L.S.B. Goldstein, M. Vershinin, M. Vershinin, M.G.L. Heuvel Van den, M.J.I. Müller, M.J.I. Müller, M.R. Evans, N. Mirin, N.A. Reed, P. Pierobon, R. Dixit, R. Lipowsky, R. Lipowsky, R. Sato-Harada, Reinhard Lipowsky, S. Heins, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Konzack, S. Lakämper, S.A. Janowsky, Stefan Klumpp, T.M. Nieuwenhuizen, Yan Chai   +52 more
core   +3 more sources