Results 151 to 160 of about 12,857 (194)
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Neurodegenerative Tauopathies

Annual Review of Neuroscience, 2001
▪ Abstract  The defining neuropathological characteristics of Alzheimer's disease are abundant filamentous tau lesions and deposits of fibrillar amyloid β peptides. Prominent filamentous tau inclusions and brain degeneration in the absence of β-amyloid deposits are also hallmarks of neurodegenerative tauopathies exemplified by sporadic corticobasal ...
V M, Lee, M, Goedert, J Q, Trojanowski
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The tauopathies

2023
Tauopathies are a clinically and neuropathologically heterogeneous group of neurodegenerative disorders, characterized by abnormal tau aggregates. Tau, a microtubule-associated protein, is important for cytoskeletal structure and intracellular transport.
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Update on tauopathies

Current Opinion in Neurology, 2017
Purpose of review The purpose of this review is to provide an update on the role of tau beyond the stabilization of microtubules and on the clinical, pathological, diagnostic and therapeutic aspects of tauopathies. Recent findings Beyond its function as a microtubule-associated tau ...
Thibaud, Lebouvier   +2 more
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Tau and Tauopathies

Neurology India, 2007
Tau protein is a neuronal microtubule-associated protein (MAP), which localizes primarily in the axon. It is one of the major and most widely distributed MAPs in the central nervous system. Its biochemistry and molecular pathology is being increasingly studied. Tau is a key component of neurofbrillary tangles in Alzheimer's disease (AD). Disorders with
Mathuranath, PS, Robert, M
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