Results 91 to 100 of about 102,843 (325)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu   +6 more
wiley   +1 more source

Taurine increases hippocampal neurogenesis in aging mice

open access: yesStem Cell Research, 2015
Aging is associated with increased inflammation and reduced hippocampal neurogenesis, which may in turn contribute to cognitive impairment. Taurine is a free amino acid found in numerous diets, with anti-inflammatory properties.
Elias Gebara   +3 more
doaj   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira   +9 more
wiley   +1 more source

Fish larval nutrition and feed formulation: knowledge gaps and bottlenecks for advances in larval rearing [PDF]

open access: yes, 2013
Despite considerable progress in recent years, many questions regarding fish larval nutrition remain largely unanswered, and several research avenues remain open.
Applebaum   +251 more
core   +3 more sources

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad   +12 more
wiley   +1 more source

Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]

open access: yes, 2014
Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran   +5 more
core   +2 more sources

Simultaneous Detection of GABA and Glycine Using MEGA‐PRESS With TE Optimization at 3T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To achieve the simultaneous acquisition of gamma‐aminobutyric acid (GABA) and glycine (Gly) using a MEGA‐PRESS sequence with an optimized TE at 3T. Methods MEGA‐PRESS simulations were performed at TEs 60‐88 ms to determine the optimal TE for Gly detection with minimal myo‐Inositol (mI) overlap and maximal GABA detection sensitivity ...
Justin R. Singer, Kimberly L. Chan
wiley   +1 more source

Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice

open access: yesJournal of Biomedical Science, 2010
Taurine, a sulfur-containing β-amino acid, is highly contained in heart and skeletal muscle. Taurine has a variety of biological actions, such as ion movement, calcium handling and cytoprotection in the cardiac and skeletal muscles.
Ito Takashi   +7 more
doaj   +1 more source

Potential protective role of reactive astrocytes in the periventricular parenchyma in congenital hydrocephalus [PDF]

open access: yes, 2016
Background Cerebrospinal fluid accumulation in hydrocephalus produces an elevation of intraventricular pressure with pathological consequences on the periventricular brain parenchyma including ischemia, oedema, oxidative stress, and accumulation of ...
Alonso-Carrion, Francisco Jose   +9 more
core  

Home - About - Disclaimer - Privacy