Results 191 to 200 of about 102,843 (325)

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen   +17 more
wiley   +1 more source

Indian‐enriched genetic variants are associated with cognitive function

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Little is known about genetic risk factors for dementia in South Asians. Examining genetic variants that occur at higher frequency in India compared to other ancestries (i.e., Indian enriched variants) may identify genetic associations with cognitive function that are potentially unique to the Indian population.
Hasan Abu‐Amara   +12 more
wiley   +1 more source

Table 1_Palmatine potentiates cefquinome efficacy against multidrug-resistant Escherichia coli via sulfur/taurine metabolism and oxidative stress modulation.docx

open access: green
Yining Zhang (532481)   +12 more
openalex   +1 more source

Female‐biased astrocytic priming shapes early locus coeruleus vulnerability in an Aβ oligomer milieu

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The locus coeruleus (LC) is an early site of Alzheimer's disease (AD) pathology, yet the role of brainstem astrocytes in early, sex‐dependent vulnerability remains unclear. METHODS In 2‐ to 3‐month‐old APP/PS1 mice, we combined in vivo proton magnetic resonance spectroscopy (MRS) of the brainstem with region‐resolved molecular ...
Srishti Kushwaha   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy