Results 191 to 200 of about 102,843 (325)
Temporal Urinary Metabolomic Profiling in ICU Patients with Critical COVID-19: A Pilot Study Providing Insights into Prognostic Biomarkers via 1H-NMR Spectroscopy. [PDF]
Matpan E +4 more
europepmc +1 more source
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen +17 more
wiley +1 more source
Taurine Attenuates M1 Macrophage Polarization and IL-1β Production by Suppressing the JAK1/2-STAT1 Pathway via Metabolic Reprogramming. [PDF]
Zhang Z +11 more
europepmc +1 more source
Molecular Mechanism of the K v 7.1-Channel Activator N-Arachidonoyl Taurine [PDF]
Sara I. Liin +2 more
openalex +1 more source
Indian‐enriched genetic variants are associated with cognitive function
Abstract INTRODUCTION Little is known about genetic risk factors for dementia in South Asians. Examining genetic variants that occur at higher frequency in India compared to other ancestries (i.e., Indian enriched variants) may identify genetic associations with cognitive function that are potentially unique to the Indian population.
Hasan Abu‐Amara +12 more
wiley +1 more source
Taurine Alleviates Inflammation, Oxidative Stress, Apoptosis, and Uterus Microbiota Dysregulation of Endometritis by Inhibiting PI3K-AKT/MAPK/NF-κB Pathways in Mice. [PDF]
Xiao J +9 more
europepmc +1 more source
Female‐biased astrocytic priming shapes early locus coeruleus vulnerability in an Aβ oligomer milieu
Abstract INTRODUCTION The locus coeruleus (LC) is an early site of Alzheimer's disease (AD) pathology, yet the role of brainstem astrocytes in early, sex‐dependent vulnerability remains unclear. METHODS In 2‐ to 3‐month‐old APP/PS1 mice, we combined in vivo proton magnetic resonance spectroscopy (MRS) of the brainstem with region‐resolved molecular ...
Srishti Kushwaha +4 more
wiley +1 more source

