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Fibre composition in sow diets influences bile acid profile in colostrum and in intestinal digesta of their new-born suckling piglets. [PDF]

J Nutr Sci
Grześkowiak ŁM, Ipharraguerre IR, Rimbach G, Vahjen W, Zentek J.   +4 more
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Effects of taurocholic acid on immunoregulation in mice

International Immunopharmacology, 2013
Currently, there is a dramatically growing interest in Chinese traditional medicines, especially in the therapy of inflammatory diseases. Taurocholic acid (TCA), as a kind of natural bioactive substance of animal bile acid, has medicinal applications to treat a wide range of inflammatory diseases.The study was designed to evaluate the effects of TCA on
Lei Li, Chang Liu, Chenguang Du
exaly   +3 more sources

Diabetes development increased concentrations of the conjugated bile acid, taurocholic acid in serum, while treatment with microencapsulated-taurocholic acid exerted no hypoglycaemic effects

European Journal of Pharmaceutical Sciences, 2017
The bile acid taurocholic acid (TCA) is endogenously produced, and has shown formulation-stabilising effects when incorporated into microcapsules containing potential antidiabetic drugs. This study aimed to develop and characterise TCA-microcapsules, and test their antidiabetic effects, in an animal model of Type 1 diabetes (T1D).Using the polymer ...
Momir Mikov, Svetlana Golocorbin-Kon, Hani Al-Salami   +2 more
exaly   +4 more sources

Effects of taurocholic acid on gastric acid secretion and gastrin release

Gastroenterology, 1980
Abstract Serum gastrin concentrations and Heidenhain pouch acid outputs were measured in dogs before and during perfusion of denervated antral pouches with 10 mM taurocholic acid. Perfusates were maintained at an osmolality of 300 mosM, with pH adjusted to 7.0, 3.0, or 1.0.
T, Sekine, E R, Woodward, J E, McGuigan
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Renal excretion of bile acids: taurocholic, glycocholic, and cholic acids

American Journal of Physiology-Legacy Content, 1964
The renal clearance (in dogs) of taurocholate, after correction for plasma-protein binding, is less than the glomerular filtration rate. Clearance increases toward, but does not attain, the filtration rate as filtered load is increased. Clearance is not influenced by changes in urinary pH or flow, nor by administration of probenecid or benzmalecene ...
I M, WEINER, J E, GLASSER, L, LACK
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THE HEPATIC TRANSPORT OF TAUROCHOLIC ACID IN THE RAT: DEVELOPMENT OF A MATHEMATICAL MODEL

Clinical and Experimental Pharmacology and Physiology, 1976
1. The transport of taurocholic acid from portal blood to bile was studied in the anaesthetized rat by injecting a radiolabelled pulse of bile acid. 2. The transport process was very rapid, 50% of the dose being secreted within 5 min, and the total dose within 15 min. 3. The transport process had a large capacity.
R A Smallwood, N E Hoffman
exaly   +3 more sources

Effect of Phenobarbital on the Conversion of Cholesterol to Taurocholic Acid

European Journal of Biochemistry, 1968
The effect of administration of phenobarbital to rats on four different enzyme systems in the metabolic pathway from cholesterol to taurocholic acid, on the metabolism of androst‐4‐ene‐3,17‐dione, and on the oxidative demethylation of aminopyrine was studied in liver homogenates.
K, Einarsson, G, Johansson
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Altered hepatobiliary transport of taurocholic acid in aged rats

Mechanisms of Ageing and Development, 1980
Hepatobiliary transport of taurocholic acid was studied in adult (3 months) and old (2 years) rats using an isolated perfused rat liver technique in order to determine the effect of age on hepatic uptake and secretion of bile acids simultaneously. The results were analyzed using a steady-state compartmental model to estimate the uptake and secretion of
R, Kroker, D, Hegner, M S, Anwer
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Effect of Dehydrocholic, Chenodeoxycholic, and Taurocholic Acids on the Excretion of Bilirubin

American Journal of Veterinary Research, 1980
SUMMARY The effects of iv bile acid infusion (at approx 20% of normal excretion rate) on the biliary excretion of 3-α-hydroxy bile acids and bilirubin were investigated in ponies prepared surgically with chronic external biliary fistulas. Endogenous bile acid excretion (approx 45 µmol/min) decreased to the hepatic synthesis rate (approx 1.5 µmol/min ...
L R, Engelking, R, Gronwall, M S, Anwer
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