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Insulin-like peptide 5 is released in response to bile acid in the rectum and is associated with diarrhoea severity in patients with bile acid diarrhoea. [PDF]

open access: yesGut
Bannon CA   +14 more
europepmc   +1 more source

Plasma Metabolomic and Proteomic Signatures of Blood Pressure Management After Bariatric Surgery Among Adolescents. [PDF]

open access: yesHypertension
Pan S   +22 more
europepmc   +1 more source
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Effects of taurocholic acid on immunoregulation in mice

International Immunopharmacology, 2013
Currently, there is a dramatically growing interest in Chinese traditional medicines, especially in the therapy of inflammatory diseases. Taurocholic acid (TCA), as a kind of natural bioactive substance of animal bile acid, has medicinal applications to treat a wide range of inflammatory diseases.The study was designed to evaluate the effects of TCA on
Chang Liu, Lei Li, Peifeng Li
exaly   +3 more sources

THE HEPATIC TRANSPORT OF TAUROCHOLIC ACID IN THE RAT: DEVELOPMENT OF A MATHEMATICAL MODEL

Clinical and Experimental Pharmacology and Physiology, 1976
1. The transport of taurocholic acid from portal blood to bile was studied in the anaesthetized rat by injecting a radiolabelled pulse of bile acid. 2. The transport process was very rapid, 50% of the dose being secreted within 5 min, and the total dose within 15 min. 3. The transport process had a large capacity.
J H, Iser   +3 more
exaly   +3 more sources

Taurocholic acid inhibits features of age-related macular degeneration in vitro

Experimental Eye Research, 2020
Previous metabolomics studies from our lab found altered plasma levels of bile acids in patients with age-related macular degeneration (AMD) compared to controls. In this study, we investigated the ability of the bile acid taurocholic acid (TCA) to inhibit features of AMD modeled in vitro. Paraquat was used to induce oxidative stress in HRPEpiC primary
Joshua Barnett, Milam A Brantley
exaly   +3 more sources

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