Results 131 to 140 of about 6,894 (164)
Some of the next articles are maybe not open access.
Effect of pirenzepine and PGE2 on taurocholic acid-induced gastric lesions
Pharmacological Research Communications, 1986Cytoprotective activity of Pirenzepine (PZ) and Prostaglandin E2 (PGE2) was investigated in the gastric damage induced by taurocholic acid (TA) in the rat. Gastric mucosal potential difference (PD) and gross mucosal erosions were measured. Intravenous PZ (18 mg/kg) and PGE2 (5 micrograms/kg) prevented both the sharp decrease of PD and the gastric ...
L, Varin, A, Giachetti, A, Brambilla
openaire +2 more sources
Inhibition of the synthesis of taurocholic acid by structural analogues of taurine
Biochemical Pharmacology, 1977Abstract Structural analogues of taurine that are inhibitors of the rat liver microsomal synthesis of taurocholic acid are reported. Isethionic acid, the hydroxy analogue of taurine, is the most potent inhibitor ( I 50 = 110 μM ). Aminomethanesulfonic acid, a taurine analogue which has a single carbon bridge between the amino and sulfonic acid ...
openaire +2 more sources
Only free bile acid drives ileal absorption of taurocholate
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1986We compared the intestinal absorption of monomeric taurocholate bound to albumin with the absorption of the free form. In the presence of albumin the apparent uptake coefficient is about three times greater than that in its absence. This result resembles the one reported previously for the liver. In the gut, however, this phenomenon is attributable to
B A, Luxon, P D, King, E L, Forker
openaire +2 more sources
Intestinal Taurine and the Enterohepatic Circulation of Taurocholic Acid in the Cat
1992Taurine’s most well defined role is the conjugation of bile salts in the liver. After synthesis from cholesterol, bile salts are conjugated with taurine and/or glycine before secretion into the bile canaliculi1. When taurine is limiting, most mammals have the ability to conjugate bile salts with glycine, exceptions being the dog2 and the cat3,4, which ...
M A, Hickman, J G, Morris, Q R, Rogers
openaire +2 more sources
Uptake of taurocholic acid and cholic acid in isolated hepatocytes from rainbow trout
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1994The uptake of the bile acids cholate (CHA) and taurocholate (TCHA) was studied in isolated hepatocytes from rainbow trout (Oncorhynchus mykiss). Both CHA and TCHA were taken up in a concentration- and temperature-dependent manner with optimum temperature at 15 degrees C and a strikingly efficient uptake even at low temperatures (0-5 degrees C).
C M, Råbergh +4 more
openaire +2 more sources
Transhepatic transport of taurocholic acid in normal and mutant analbuminemic rats
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1985To elucidate a possible function of plasma albumin in vectorial transport of various cholephilic organic anions, such as bile acids, plasma clearance and transhepatic transport of radioactive taurocholate were studied in vivo in normal and mutant analbuminemic rats. Intravenous administration of taurocholate was followed by its rapid disappearance from
M, Inoue, Y, Morino, S, Nagase
openaire +2 more sources
Signal transduction for taurocholic acid in the olfactory system of Atlantic salmon
Chemical Senses, 1994Conjugated bile acids such as taurocholic acid (TChA) are potent olfactory stimuli for Atlantic salmon (Salmo salar). A plasma membrane rich fraction was derived from salmon olfactory rosettes and used to investigate TChA signal transduction and receptor binding.
Lo, Ying Har +5 more
openaire +3 more sources
Gastroenterology, 1988
The "apparent" fractional turnover rate of the gamma-labeled bile acid analogue 75selenohomocholic acid-taurine (75SeHCAT) was assessed from decline in radioactivity over the gallbladder area on 4 successive days using a gamma-camera, and was compared in the same subjects with the fractional turnover rate of the corresponding natural bile acid, cholic ...
R P, Jazrawi +3 more
openaire +2 more sources
The "apparent" fractional turnover rate of the gamma-labeled bile acid analogue 75selenohomocholic acid-taurine (75SeHCAT) was assessed from decline in radioactivity over the gallbladder area on 4 successive days using a gamma-camera, and was compared in the same subjects with the fractional turnover rate of the corresponding natural bile acid, cholic ...
R P, Jazrawi +3 more
openaire +2 more sources
Effects of gemfibrozil and clofibric acid on the uptake of taurocholate by isolated rat hepatocytes
Biochemical Pharmacology, 1997Clinical use of fibrate hypolipidaemic agents has been associated with an increased incidence of hepatobiliary dysfunction including increased bile lithogenicity, gallstone formation, and cholestasis. The hepatic transport of bile acids plays an important role in bile formation and flow, and interference with the hepatocellular transport of bile acids ...
Sabordo, L., Sallustio, B.
openaire +3 more sources
Chymotrypsin esterase activity in the presence of oleic and taurocholic acid
Biochimica et Biophysica Acta (BBA) - Enzymology, 1968A I, Rogers, P S, Bachorik
openaire +2 more sources