Results 81 to 90 of about 6,842 (160)

Metabolomic profiles differentiate between porto-sinusoidal vascular disorder, cirrhosis, and healthy individuals

JHEP Reports
Background & Aims: Porto-sinusoidal vascular disorder (PSVD) is a rare and diagnostically challenging vascular liver disease. This study aimed to identify distinct metabolomic signatures in patients with PSVD or cirrhosis to facilitate non-invasive ...
Georg Semmler, Oleksandr Petrenko, Juanjo Jose Lozano, Sarah Shalaby, Juan I. Sánchez-Avila, Nara Marella, Thomas Hannich, Katharina Wöran, Lorenz Balcar, Benedikt Simbrunner, Katharina Lampichler, Behrang Mozayani, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Juan-Carlos García-Pagán, Bernhard Scheiner   +16 more
doaj   +1 more source

Cholesterol assimilation, acid and bile survival of probiotic bacteria isolated from food and reference strains

CyTA - Journal of Food, 2018
The evidence shows that probiotics can reduce cardiovascular diseases associated to high cholesterol levels, but it occurs just when they survive gastrointestinal conditions. The aim of this study was to evaluate the ability of reference strains (RS) and
Martha Montserrat Castorena-Alba, Jesús Alberto Vázquez-Rodríguez, Manuel López-Cabanillas Lomelí, Blanca Edelia González-Martínez   +3 more
doaj   +1 more source

CYP2D6 Activity Is Correlated with Changes in Plasma Concentrations of Taurocholic Acid during Pregnancy and Postpartum in CYP2D6 Extensive Metabolizers. [PDF]

Drug Metab Dispos, 2023
Czuba LC, Malhotra K, Enthoven L, Fay EE, Moreni SL, Mao J, Shi Y, Huang W, Totah RA, Isoherranen N, Hebert MF.   +10 more
europepmc   +1 more source

High-concentrate diet decreases lamb fatty acid contents by regulating bile acid composition

Food Chemistry: X
Feeding sheep with high-concentrate diet (HCD) to shorten production cycle is a well-developed feeding strategy to increase lamb production. Here, metabolomics were performed to explore the mechanism that HCD changes lamb nutrition composition ...
Kaizhi Zheng, Liangyong Guo, Yang Cao, Yuyang Yin, Hui Gao, Xiaowei Zhang, Junfang Jiang, Jinbing Li, Xin Huang, Kui Li, Sangang He   +10 more
doaj   +1 more source

Bile acids segregate metabolic syndrome in a cohort of 100 deeply phenotyped horses

Communications Biology
Metabolic syndrome (MetS)—encompassing obesity, insulin resistance, dyslipidemia, and hypertension—is prevalent in both humans and horses, offering a unique opportunity to explore shared pathophysiological mechanisms across species in a controlled model ...
Callum G. Donnelly, Sichong Peng, Lance Pflieger, Jane Manfredi, Michele Coleman, Noa Rappaport, Nathan D. Price, Carrie J. Finno   +7 more
doaj   +1 more source

ABCA8-mediated efflux of taurocholic acid contributes to gemcitabine insensitivity in human pancreatic cancer via the S1PR2-ERK pathway. [PDF]

Cell Death Discov, 2021
Yang C, Yuan H, Gu J, Xu D, Wang M, Qiao J, Yang X, Zhang J, Yao M, Gu J, Tu H, Gan Y.   +11 more
europepmc   +1 more source

The enzymic synthesis of taurocholic acid: a qualitative study [PDF]

Biochemical Journal, 1956
openaire   +2 more sources

Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8⁺ T and NK cell function. [PDF]

Cell Mol Immunol, 2021
Xun Z, Lin J, Yu Q, Liu C, Huang J, Shang H, Guo J, Ye Y, Wu W, Zeng Y, Wu S, Xu S, Chen T, Chen J, Ou Q.   +14 more
europepmc   +1 more source

Bile acids as potential pheromones in pintado catfish Pseudoplatystoma corruscans (Spix & Agassiz, 1829): eletrophysiological and behavioral studies

Neotropical Ichthyology
Bile acids are potent olfactory and gustatory stimulants for fish. Electro-olfactogram recording was used to test whether the olfactory epithelium of pintado catfish Pseudoplatystoma corruscans is specifically sensitive to bile acids, some of which have ...
Percília Cardoso Giaquinto, Rodrigo Egydio Barreto, Gilson Luiz Volpato, Marisa Fernandes-de-Castilho, Eliane Gonçalves-de-Freitas   +4 more
doaj   +1 more source

STUDIES ON THE PRODUCTION OF TAUROCHOLIC ACID IN THE DOG

Journal of Biological Chemistry, 1937
Robert W. Virtue, Mildred E. Doster-Virtue   +1 more
openaire   +1 more source