Journal of Translational MedicineBackground Chronic liver diseases (CLDs) are pervasive health issue worldwide, whereas radiation-induced intestinal injury is a frequent and consequential complication of abdominopelvic radiotherapy.
Bin Wang +9 more
doaj +1 more source
The Effect of Sodium Benzoate and Taurocholic Acid Feeding on Human Bile Composition
Experimental Biology and Medicine, 1975 Four patients were fed sodium benzoate after stabilization following common bile duct exploration. Bile collections revealed no change in the output of glycine conjugated bile acids. Three patients had taurocholic acid added to the regimen after 3 days and demonstrated a significant increase in total and taurine conjugated bile acid output with marked ...
C, Dennis +3 more
openaire +2 more sources
JHEP ReportsBackground & Aims: Porto-sinusoidal vascular disorder (PSVD) is a rare and diagnostically challenging vascular liver disease. This study aimed to identify distinct metabolomic signatures in patients with PSVD or cirrhosis to facilitate non-invasive ...
Georg Semmler +16 more
doaj +1 more source
CyTA - Journal of Food, 2018 The evidence shows that probiotics can reduce cardiovascular diseases associated to high cholesterol levels, but it occurs just when they survive gastrointestinal conditions. The aim of this study was to evaluate the ability of reference strains (RS) and
Martha Montserrat Castorena-Alba +3 more
doaj +1 more source
CYP2D6 Activity Is Correlated with Changes in Plasma Concentrations of Taurocholic Acid during Pregnancy and Postpartum in CYP2D6 Extensive Metabolizers. [PDF]
Drug Metab Dispos, 2023 Czuba LC +10 more
europepmc +1 more source
High-concentrate diet decreases lamb fatty acid contents by regulating bile acid composition
Food Chemistry: XFeeding sheep with high-concentrate diet (HCD) to shorten production cycle is a well-developed feeding strategy to increase lamb production. Here, metabolomics were performed to explore the mechanism that HCD changes lamb nutrition composition ...
Kaizhi Zheng +10 more
doaj +1 more source
Bile acids segregate metabolic syndrome in a cohort of 100 deeply phenotyped horses
Communications BiologyMetabolic syndrome (MetS)—encompassing obesity, insulin resistance, dyslipidemia, and hypertension—is prevalent in both humans and horses, offering a unique opportunity to explore shared pathophysiological mechanisms across species in a controlled model ...
Callum G. Donnelly +7 more
doaj +1 more source
The enzymic synthesis of taurocholic acid: a qualitative study [PDF]
Biochemical Journal, 1956 openaire +2 more sources
ABCA8-mediated efflux of taurocholic acid contributes to gemcitabine insensitivity in human pancreatic cancer via the S1PR2-ERK pathway. [PDF]
Cell Death Discov, 2021 Yang C +11 more
europepmc +1 more source
Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function. [PDF]
Cell Mol Immunol, 2021 Xun Z +14 more
europepmc +1 more source