De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes [PDF]
Background Euphorbia fischeriana is an important medicinal plant found in Northeast China. The plant roots contain many medicinal compounds including 12-deoxyphorbol-13-acetate, commonly known as prostratin that is a phorbol ester from the tigliane ...
Barrero Roberto A +29 more
core +2 more sources
Assembly of the eukaryotic PLP-synthase complex from plasmodium and activation of the Pdx1 enzyme [PDF]
Biosynthesis of vitamins is fundamental to malaria parasites. Plasmodia synthesize the active form of vitamin B6 (pyridoxal 5-phosphate, PLP) using a PLP synthase complex.
Böttcher, Bettina +9 more
core +1 more source
Glucan synthase of Phytophthora sojae [PDF]
Glucans, with the (1-3)-b-glucosidic linkage as major feature, are present in most of the higher plants, in many lower plants, as well as in microorganisms (Stone and Clarke, 1992). The synthesis of (1-3)-b-glucan in vivo is catalysed by the enzyme (1-3)-
Antelo, Luis
core +1 more source
Improved taxadiene production by optimizing DXS expression and fusing short-chain prenyltransferases [PDF]
This study highlights the significance of overexpressing 1-deoxy-d-xylulose-5-phosphate synthase (DXS) from the MEP (methylerythritol 4-phosphate) pathway, in addition to short-chain prenyltransferase fusions for the improved production of the diterpene,
He, Siqi; id_orcid +4 more
core +1 more source
The Trypanosoma brucei sphingolipid synthase, an essential enzyme and a drug target [PDF]
Sphingolipids are important structural components of eukaryotic membranes, in addition they and their precursors are involved in signal transduction processes.
Pan, Ssu-Ying
core
Spatial distribution of isoprenoid enzymes and MpABCG1 transporter influences sesquiterpene accumulation in Marchantia polymorpha oil bodies. [PDF]
Forestier ECF +5 more
europepmc +1 more source
Engineered microorganisms unlock a new era of diterpenoid biomanufacturing: recent advances and future perspectives. [PDF]
Han Y +6 more
europepmc +1 more source
Designing an oxidase toolbox for site-directed oxidation of taxanes. [PDF]
Lai M +11 more
europepmc +1 more source
Diterpenoids in medicinal plants: structure, distribution, biological activities, biosynthesis, and bioengineering prospects. [PDF]
Zou X, Cheng Y, Chen X.
europepmc +1 more source
AI-Assisted Spatial Metabolic Engineering in Plants: Integrating Flux Design, Spatial Omics, and Synthetic Biology. [PDF]
Chen H, Yang J, Du M.
europepmc +1 more source

