Results 111 to 120 of about 31,972 (221)

Investigations of the chemistry of taxol

, 2005
Several C-7 and C-13 diazirinyl taxol analogs have been synthesized as potential photoaffinity-labeled derivatives for studying the nature of the binding site of taxol on polymerized tubulin.
Rimoldi, John M.
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Taxol (paclitaxel) - An antitumor drug

, 2011
Taksol je jedan od najvažnijih lijekova dobivenih iz biljaka, a koristi se u kemoterapiji kao antikancerogeni spoj. Taksol je aktivna komponenta nekoliko kemoterapeutika, a postoje i derivati taksola sa sličnim ili poboljšanim djelovanjem.
Tomasović, Ante
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Le taxol et ses nouvelles sources d'approvisionnement

, 1999
Le taxol est un agent anticancéreux d'origine naturelle issu de l'écorce de l'if du Pacifique, Taxus brevifolia. Devant les faibles quantités extraites, les chercheurs ont dû se tourner vers d'autres moyens de production.
Mahier, Sophie
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Over - expression Effect of Gene Encoding 3-hydroxy-3-Methylglutaryl-CoA Reductase on Production of Taxol in Iranian Hazel (Corylus avellana L.)

Journal of Medicinal Plants, 2013
Background: Sustainable and commercial production of taxol as an anti cancer drug is a critical point to its clinical application. Nowadays, hazel because of rapid growth and wide range distribution is considered as an alternative source of Taxol ...
A Qaderi, M Omidi, AR Zebarjadi, R Hajiaghaee   +3 more
doaj  

Taxol Production Taxusspp. Cell Culture:Semisynthesis of Taxol from Baccatin Ⅲ in Cell Cultures of Taxus baccata Pendula

, 1996
유럽 주목(Taxus baccata Pendula) 의 세포배양에 서 추출한 taxol 전구체 baccatin ill를 이용하여 항암제 taxol을 반합성할 수 있었다. 유럽주목의 캘러 스배양과 현탁배양 모두에셔 baccatin ill의 생성을 확인할 수 있었으며 함량은 건조중량 기준으로 평균 0.015%(w/w)에 달하였다. Taxol의 반합성은 세포 배양에서 생성된 baccatin ill에 taxol side chain을 합성시킴으로서 가능하였다.
정헌관, 전정욱, 김동일, 조병관, 문원종, 변상요   +5 more
core  

Gender-Specific Behavior Reductions in Spontaneous Locomotive and Rearing in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy: A Pilot Study. [PDF]

J Pain Res
Kim SJ, Cao K, Dougherty PM, McDonough KE, Javed S.   +4 more
europepmc   +1 more source

Oscillatory dynamics in paclitaxel-proteinoid networks. [PDF]

Discov Mol
Mougkogiannis P, Adamatzky A.
europepmc   +1 more source

Anti-hepatoma activity of taxol in vitro

, 2000
AIM: To investigate the in vitro anti-hepatoma activity of taxol against SMMC-7721 human hepatoma cells. METHODS: The hepatoma cell growth was measured by MTT-microculture tetrazolium assay.
Luo, Dan, Wang, Xing Wang, Xie, Hong, Yuan, Jin Hui, Xie, Yong   +4 more
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Recent paclitaxel formulation strategies: expanding the therapeutic index by addressing biopharmaceutical and toxicity limitations. [PDF]

Arch Pharm Res
Lee J, Choi MK, Song IS.
europepmc   +1 more source

Syntheses and Bioactivities of Targeted and Conformationally Restrained Taxol Analogs

, 2004
Taxol (1) was first isolated from the bark of the Pacific yew about 35 years ago by Drs. Wall and Wani. Although its development as an anticancer agent was delayed by numerous reasons, including its scarcity and insolubility, the discovery of its tubulin-
Liu, Changhui
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