Results 101 to 110 of about 31,992 (181)
Microtubule polarity in taxol-treated isolated spindles [PDF]
, 1985 Spindles were isolated from Spisula oocytes in the presence or absence of taxol to determine if cell lysis procedures previously used to analyze spindle microtubule polarity may have resulted in the loss of any microtubules of a particular polarity ...
Leah T. Haimo
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PLoS ONE, 2019 Salicylic acid (SA) is an effective elicitor to increase taxol production in Pestalotiopsis microspora. Addition of SA at the concentration of 300 μM yielded taxol 625.47 μg L-1, 45- fold higher than that of the control.
Kamalraj Subban +4 more
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Water soluble analogs and prodrugs of taxol [PDF]
, 1992 Substituted 2'-benzoyl and 2', 7-dibenzoyl taxol derivatives are synthesized which have improved water solubility and stability while maintaining bioactivity.
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Improving 10-deacetylbaccatin III-10-β-O-acetyltransferase catalytic fitness for Taxol production
Nature Communications, 2017 Taxol is a widely used anticancer drug that is found in very low amounts in the bark of Taxus plants. Here, the authors improve the catalytic fitness of DBAT, an enzyme that catalyses the conversion of tree by products into taxol, enabling the design of ...
Bing-Juan Li +6 more
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Investigations of the chemistry of taxol [PDF]
, 2005 Several C-7 and C-13 diazirinyl taxol analogs have been synthesized as potential photoaffinity-labeled derivatives for studying the nature of the binding site of taxol on polymerized tubulin.
Rimoldi, John M.
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The Cytotoxic Effects of Silymarin on the 4T1 Cell Line Derived from BALB/c Mice Mammary Tumors
Journal of Medicinal Plants, 2014 Background: There is an increasing interest in identifying potent cancer preventive and therapeutic agents. Silymarin is a flavonoids complex extracted from the milk thistle (Silybum marianum L.) seeds.
SMA Shariatzadeh +4 more
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Taxol (paclitaxel) - An antitumor drug [PDF]
, 2011 Taksol je jedan od najvažnijih lijekova dobivenih iz biljaka, a koristi se u kemoterapiji kao antikancerogeni spoj. Taksol je aktivna komponenta nekoliko kemoterapeutika, a postoje i derivati taksola sa sličnim ili poboljšanim djelovanjem.
Tomasović, Ante
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Cell Communication and SignalingBackground The release of extracellular vesicles (EVs) including exosomes from human mesenchymal stroma/stem-like cells (MSC) represents valuable cell-free carriers for the delivery of regenerative and medicinal compounds.
Ralf Hass +2 more
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Le taxol et ses nouvelles sources d'approvisionnement [PDF]
, 1999 Le taxol est un agent anticancéreux d'origine naturelle issu de l'écorce de l'if du Pacifique, Taxus brevifolia. Devant les faibles quantités extraites, les chercheurs ont dû se tourner vers d'autres moyens de production.
Mahier, Sophie
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Taxol Production Taxusspp. Cell Culture:Semisynthesis of Taxol from Baccatin Ⅲ in Cell Cultures of Taxus baccata Pendula [PDF]
, 1996 유럽 주목(Taxus baccata Pendula) 의 세포배양에 서 추출한 taxol 전구체 baccatin ill를 이용하여 항암제 taxol을 반합성할 수 있었다. 유럽주목의 캘러 스배양과 현탁배양 모두에셔 baccatin ill의 생성을 확인할 수 있었으며 함량은 건조중량 기준으로 평균 0.015%(w/w)에 달하였다. Taxol의 반합성은 세포 배양에서 생성된 baccatin ill에 taxol side chain을 합성시킴으로서 가능하였다.
정헌관 +5 more
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