Results 101 to 110 of about 31,972 (221)
Tau protein distribution after BDNF, taxol and taxol+BDNF treatment.
, 2014 (A) Tau protein distribution in control E18 hippocampal neurons. Arrow indicates the tau staining in the soma in the merged column and the α-tubulin staining of neurite dendrites in the tubulin column separately.
Lei Zhang (38117) +5 more
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Cell Communication and SignalingBackground The release of extracellular vesicles (EVs) including exosomes from human mesenchymal stroma/stem-like cells (MSC) represents valuable cell-free carriers for the delivery of regenerative and medicinal compounds.
Ralf Hass +2 more
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Studies the biological behaviors of taxol derivatives
, 1997 임상병리학과/석사[한글] 본 연구에서는 항암제인 taxol의 방사성표지화합물을 합성하여 임상적 이용 가능성을 보기 위한 기초 연구로서, 관련 화합물들의 in vitro와 in vivo에서 물리화학적, 생물학적 특성과 거동을 보았다. Taxol 구조에서 C-13의 곁가지에 있는 C-2' 부분의 bydroxyl기를 DTPA anhydride 및 succinic anhydride와 반응시켜 taxol-DTPA와 2'-hemisuccinyltaxol을 ...
유대용
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, 2005 Inabilities to attain adequate aqueous solubility and stability have made the preparation of a clinically suitable formulation of taxol difficult. Addition of nicotinamide (ND), 2-hydroxypropyl-b-cyclodextrin (HPßCD), polyethylene glycol, (PEG), bile ...
Daneshtala, Mohsen +4 more
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Short synthetic route to taxol and taxol derivatives
, 1996 A short route to the total synthesis of the core skeleton of the taxol ring system is described. The same sequence of transformations can be carried out to make the 7-hydroxy series, and connect the additional carbon atoms required for the A-ring. The number of steps to the taxane skeleton is 13, making it the shortest route from readily available ...
openaire +2 more sources
How does taxol stabilize microtubules?
, 1995 Background: The antimitotic agent taxol is an important new drug for the treatment of certain cancers. It blocks the cell cycle in its G1 or M phases by stabilizing the microtubule cytoskeleton against depolymerization.Results We have used electron ...
Wade, Richard H., Arnal, Isabelle
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, 2013 Fungal production of the anti-tumor taxol is an effective way of making this drug in industries. We reported here a new taxol-producing fungus, NK101, from plant debris in the soil.
Pan, J +5 more
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Hazel (Corylus avellana L.) as a New Source of Taxol and Taxanes
Journal of Medicinal Plants, 2012 Taxol is used to treatment of variety cancers including ovarian, breast, lung, head and neck carcinomas and the AIDS-related Karposi’s carcinoma, and was originally obtained from bark of taxus brevifolia.
A Qaderi +6 more
doaj
Microtubule polarity in taxol-treated isolated spindles
, 1985 Spindles were isolated from Spisula oocytes in the presence or absence of taxol to determine if cell lysis procedures previously used to analyze spindle microtubule polarity may have resulted in the loss of any microtubules of a particular polarity ...
Leah T. Haimo
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Water soluble analogs and prodrugs of taxol
, 1992 Substituted 2'-benzoyl and 2', 7-dibenzoyl taxol derivatives are synthesized which have improved water solubility and stability while maintaining bioactivity.
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