Results 81 to 90 of about 31,992 (181)
Down-regulated βIII-tubulin Expression Can Reverse Paclitaxel Resistance in A549/Taxol Cells Lines
Chinese Journal of Lung Cancer, 2014 Background and objective Chemotherapy drug resistance is the primary causes of death in patients with pulmonary carcinoma which make tumor recurrence or metastasis. β-tubulin is the main cell targets of anti-microtubule drug. Increased expression of βIII-
Yinling ZHUO, Qisen GUO
doaj +1 more source
Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak +4 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, Volume 20, Issue 7, Page 1667-1693, July 2026.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Chirality, Volume 38, Issue 7, July 2026.A practical and straightforward approach to optically active erythro 3‐amino‐2‐hydroxy acids and its application to the enantioselective synthesis of 3‐phenylisoserine and of the marine natural product 3‐amino‐2‐hydroxy‐6‐methylheptanoic acid is reported.
Marilena Caporale +4 more
wiley +1 more source
Chemical Structure Data File For J. Oh's Thesis, "Synthetic studies towards taxol." [PDF]
, 2020 This Structure Data File (SDfile) is associated with the thesis: Oh, J. "Synthetic studies towards taxol." and http://library.ua.edu/vwebv/holdingsInfo?bibId=837165 It is distributed by the University of Alabama Libraries.
Scalfani, Vincent F.
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Cytoskeleton, Volume 83, Issue 7, Page 496-514, July 2026.ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos +5 more
wiley +1 more source
Water soluble derivatives of taxol [PDF]
, 1990 Sulfonated 2'-acryloyltaxol and sulfonated 2'-O-acyl acid taxol derivatives are synthesized which have improved water solubility and stability while maintaining bio-activity. In particular, 2'-[(3-sulfo-1-oxopropyl)oxy]taxol sodium salt is synthesized by
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Brevifoliol: An Ignored cousin of Taxol [PDF]
, 2018 The discovery of paclitaxel, an anticancer agent was a milestone in the path of anticancer drug discovery. After approval from FDA taxol was widely used for cancer treatment.
Uzma Faridi, Fahad Mohammed Almutairi
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Flavour and Fragrance Journal, Volume 41, Issue 4, Page 935-942, July 2026.The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira +11 more
wiley +1 more source
Tau protein distribution after BDNF, taxol and taxol+BDNF treatment. [PDF]
, 2014 (A) Tau protein distribution in control E18 hippocampal neurons. Arrow indicates the tau staining in the soma in the merged column and the α-tubulin staining of neurite dendrites in the tubulin column separately.
Lei Zhang (38117) +5 more
core +1 more source