Results 91 to 100 of about 31,992 (181)

Natural Products as Modulators of ABC Transporters in Breast Cancer

open access: yesPhytotherapy Research, Volume 40, Issue 7, Page 4611-4637, July 2026.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan   +2 more
wiley   +1 more source

Development of Ultrasound Microbubbles and Phase Shift Microbubbles in Theranostics

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 4, July/August 2026.
Microbubbles have been originally designed for diagnostic applications. Over the years, microbubbles and phase shift microbubbles have been further developed for therapeutic indications. ABSTRACT Ultrasound is widely used for diagnostic imaging and therapy.
Emmanuelle J. Meuillet, Evan C. Unger
wiley   +1 more source

Studies the biological behaviors of taxol derivatives [PDF]

open access: yes, 1997
임상병리학과/석사[한글] 본 연구에서는 항암제인 taxol의 방사성표지화합물을 합성하여 임상적 이용 가능성을 보기 위한 기초 연구로서, 관련 화합물들의 in vitro와 in vivo에서 물리화학적, 생물학적 특성과 거동을 보았다. Taxol 구조에서 C-13의 곁가지에 있는 C-2' 부분의 bydroxyl기를 DTPA anhydride 및 succinic anhydride와 반응시켜 taxol-DTPA와 2'-hemisuccinyltaxol을 ...
유대용
core  

The Effect of Temperature, pH, and Different Solubilizing Agents on Stability of Taxol: Stability of taxol in solutions [PDF]

open access: yes, 2005
Inabilities to attain adequate aqueous solubility and stability have made the preparation of a clinically suitable formulation of taxol difficult. Addition of nicotinamide (ND), 2-hydroxypropyl-b-cyclodextrin (HPßCD), polyethylene glycol, (PEG), bile ...
Daneshtala, Mohsen   +4 more
core   +1 more source

Use of endophytic fungi in the Taxol anticancer drug production

open access: yesBiotecnología Vegetal, 2014
Taxol is a drug used in the chemotherapy of breast, lung, ovarian, prostate, liver cancers, and in the treatment of rheumatoid arthritis. Taxol is obtained from Taxus spp. trees. It is found in low concentrations in the bark, needles and roots.
Hebert Jair Barrales-Cureño   +1 more
doaj  

How does taxol stabilize microtubules? [PDF]

open access: yes, 1995
Background: The antimitotic agent taxol is an important new drug for the treatment of certain cancers. It blocks the cell cycle in its G1 or M phases by stabilizing the microtubule cytoskeleton against depolymerization.Results We have used electron ...
Wade, Richard H., Arnal, Isabelle
core   +1 more source

Enhancement of Taxol production by applying amino acid complex along with chitosan in suspension culture of Taxus baccata L.

open access: yesJournal of Medicinal Plants, 2020
Background: Taxol (Paclitaxel) has been highly recommended to control and treat a wide range of cancers. Taxus baccata L. is primary and natural origin of Taxol. Objective: Due to severe restriction and prohibition of cutting T.
Bahar Amirkavei Najafabadi   +4 more
doaj  

Synthesis of Ester-linked Taxol-glycoside Conjugate and Its Application to Drug Delivery System Using Immunoliposome Targeted with Trastuzumab and Cetuximab

open access: yesNatural Product Communications, 2018
Synthesis of ester-linked glycoside prodrug of taxol, i.e., 7-glycolyltaxol 2″- O -α-D-glucopyranoside, was investigated by chemical synthetic procedure.
Hiroki Hamada   +6 more
doaj   +1 more source

Profiles and Bioinformatics Analysis of Differentially Expressed Circrnas in Taxol-Resistant Non-Small Cell Lung Cancer Cells

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Circular RNAs (circRNAs) act as microRNA (miRNA) sponges that regulate gene expression and are involved in physiological and pathological processes.
Ning Xu   +7 more
doaj   +1 more source

A new taxol-producing fungus (Pestalotiopsis malicola) and evidence for taxol as a transient product in the culture [PDF]

open access: yes, 2013
Fungal production of the anti-tumor taxol is an effective way of making this drug in industries. We reported here a new taxol-producing fungus, NK101, from plant debris in the soil.
Pan, J   +5 more
core   +2 more sources

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