The regulatory mechanism of fungal elicitor-induced secondary metabolite biosynthesis in medical plants. [PDF]
A wide range of external stress stimuli trigger plant cells to undergo complex network of reactions that ultimately lead to the synthesis and accumulation of secondary metabolites.
Cheng-jian Zheng +23 more
core +1 more source
A sigma factor toolbox for orthogonal gene expression in Escherichia coli [PDF]
, 2018 Synthetic genetic sensors and circuits enable programmable control over timing and conditions of gene expression and, as a result, are increasingly incorporated into the control of complex and multi-gene pathways.
Bervoets, Indra +6 more
core +4 more sources
Restoration of Taxol Sensitivity of Multidrug-Resistant Cells by the Cyclosporine SDZ PSC 833 and the Cyclopeptolide SDZ 280-446 [PDF]
, 2017 Background: Taxol, a promising agent for the treatment of cancer, has entered phase II clinical trials. Nevertheless, it belongs to the class of compounds that show impaired retention in multidrug-resistant cells expressing P-glycoprotein (Pgp), a drug ...
Jachez, Bénédicte +2 more
core
Natural Products from Marine Fungi—Still an Underrepresented Resource [PDF]
, 2016 Marine fungi represent a huge potential for new natural products and an increased number of new metabolites have become known over the past years, while much of the hidden potential still needs to be uncovered.
Imhoff, Johannes F.
core +2 more sources
Frontiers in Bioengineering and Biotechnology, 2019 Epothilones are a kind of macrolides with strong cytotoxicity toward cancer cells and relatively lower side effects compared with taxol. Epothilone B derivate ixabepilone has been used for the clinical treatment of advanced breast cancer.
Wei Ye +8 more
doaj +1 more source
Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action
Molecules, 2019 Specialized plant terpenoids have found fortuitous uses in medicine due to their evolutionary and biochemical selection for biological activity in animals.
Matthew E. Bergman +2 more
doaj +1 more source
Synthesis of several bisabolane sesquiterpenoids from xanthorrhizol isolated from C. Xanthorrhiza [PDF]
, 2005 Xanthorrhizol was isolated from the essential oil of fresh rhizomes of C. xanthorrhiza in 20.2% yield by fractionation using vacuum liquid chromatography. Several bisabolane-type sesquiterpenoids have been synthesised from this xanthorrhizol.
Ngai, Mun Hong
core
High Quality RNA Isolation from Leaf, Shell, Root Tissues and Callus of Hazelnut (Corylus avellana L.) [PDF]
Journal of Nuts, 2017 Extraction of high quality RNA is a critical step in molecular genetics studies. Hazelnut is one of the most important nuts plants in the world. The presence of the taxol and other taxanes in hazelnut plant necessitates explaining their biosynthesis ...
Hossein Khosravi +2 more
doaj
Pharmaceutical Crops: An Overview [PDF]
, 2010 Pharmaceutical crops is an ambiguous term used by biologists and chemists for different categories of plants. We define pharmaceutical crops as those cultivated species that are used for extraction or preparation of therapeutic substances such as active ...
Antoun, Mikhail +5 more
core +1 more source
Extracellular biosynthesis of gadolinium oxide (Gd2O3) nanoparticles, their biodistribution and bioconjugation with the chemically modified anticancer drug taxol [PDF]
, 2014 Shadab Ali Khan +2 more
openalex +1 more source