Bioresources and BioprocessingBiosynthesis of paclitaxel (Taxol™) is a hot topic with extensive and durable interests for decades. However, it is severely hindered due to the very low titers of intermediates.
Wen-Liang Xie +5 more
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Regulation Mechanism of MYC Family Transcription Factors in Jasmonic Acid Signalling Pathway on Taxol Biosynthesis. [PDF]
Int J Mol Sci, 2019 Cui Y, Mao R, Chen J, Guo Z.
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Taxol productivity and physiological relationships in suspension cultures of Taxus Cuspidata [PDF]
, 1995 1995 Fall.Includes bibliographic references (pages 143-159).Taxol, an extractive of the Pacific yew, is a plant secondary metabolite that has demonstrated anticancer activity.
Reardon, Kennete F., committee member +2 more
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Metabolic engineering for the optimal production of Taxol (Paclitaxel) - an efficient anticancer drug (focusing on upstream pathways for isoprenoid accumulation). [PDF]
, 2013 Taxol is one of the most important and active chemotherapeutic agents for clinical treatment of cancers (including ovarian, breast bladder, prostate, and lung cancers), since taxol is an anti-proliferative agent that inhibits cancer cell division ...
Ng, James Shizhao.
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BMC Plant BiologyBackground Paclitaxel (Taxol) is an invaluable secondary metabolite extracted from Taxus species, wildly utilized in cancer therapeutics. Salicylic acid (SA), an important phytohormone, substantially elevates paclitaxel accumulation in Taxus cell ...
Yifei Ren +5 more
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Advances in Functional Genomics and Biotechnology for Enhancing Therapeutic Potential of Medicinal Plants. [PDF]
Int J Mol SciZaman W, Park S.
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TAKSOL VE TÜREVLERİNİN BİYOSENTEZİ : THE BIOSYNTHESIS OF TAXOL AND DERIVATIVES
Ankara Universitesi Eczacilik Fakultesi Dergisi, 1999 Nurgün ERDEMOĞLU, Bilge ŞENER
openaire +1 more source
Advances in the microbial biosynthesis of therapeutic terpenoids. [PDF]
Curr Opin BiotechnolWinegar PH +4 more
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The early stages of taxol biosynthesis: an interim report on the synthesis and identification of early pathway metabolites. [PDF]
Nat Prod Rep, 2012 Guerra-Bubb J, Croteau R, Williams RM.
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Toward Sustainable Paclitaxel Bioproduction: Plant Biology, Biosynthesis and Platform Engineering. [PDF]
Plants (Basel)Zhang M, Xing X, Zhu H.
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