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[Advances and prospects of taxol biosynthesis by endophytic fungi].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2018Taxol is one of the most important chemotherapeutic drugs against cancer. Taxol has been mainly extracted from the bark of yews for a long time. However, methods for the extraction of taxol from the bark of Taxus species were inefficient and environmentally costly.
Kai, Zhao +6 more
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Computational Investigation of Cytochrome P450-Catalyzed Oxetane Formation in Taxol Biosynthesis
BiochemistryPaclitaxel (Taxol) is widely recognized as one of the most effective natural anticancer drugs, yet its production is limited by its scarce natural supply and the low yields obtained from its chemical synthesis. One of the most puzzling steps in its biosynthesis is the formation of the oxetane-containing D-ring, a key structural element necessary for ...
Surajit Nandi +5 more
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Sites of Biosynthesis and Storage of Taxol in Taxus media (Rehder) Plants: Mechanism of Accumulation
Phytochemistry, 2020Sameh Soliman, Manish N Raizada
exaly
Improvements in Taxol Biosynthesis by Metabolic Engineering: Recent Trends
2022Sicon Mitra +11 more
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Biosynthesis of Taxoids. Mode of Attachment of the Taxol Side Chain
Journal of the American Chemical Society, 1994Paul E. Fleming +4 more
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