Results 131 to 140 of about 507 (153)

Four New Taxanes from the Roots of Taxus yunnanensis

Journal of Natural Products, 1995
Four new taxanes were isolated from the roots of Taxus yunnanensis. Among them, two were determined to contain isobutyrate group and propionyloxy group on C-14 respectively, and one was determined as the least oxygenated taxane. The structures were elucidated by spectroscopic means.
Hongjie Zhang, Handong Sun, Yoshio Takeda   +2 more
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Multidrug Resistant Cancer Cells Susceptibility to Cytotoxic Taxane Diterpenes from Taxus yunnanensis and Taxus chinensis

Bioorganic & Medicinal Chemistry Letters, 2002
Twelve taxane diterpenes (1-12), which were isolated previously from the EtOH extract of the aerial parts of Taxus yunnanensis or Taxus chinensis, were evaluated for cytotoxicity against the multidrug resistant cancer cells KB-VIN and KB-7d. Compounds and showed significant cytotoxicity in these cell lines.
Youichi, Shinozaki, Narihiko, Fukamiya, Chieko, Uchiyama, Masayoshi, Okano, Kiyoshi, Tagahara, Kenneth F, Bastow, Kuo-Hsiung, Lee   +6 more
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Dantaxusins A and B, Two New Taxoids fromTaxus yunnanensis

Journal of Natural Products, 2001
Two new taxane diterpenes, dantaxusin A [5 alpha-cinnamoyloxy-2 alpha,7 beta,13 alpha-triacetoxy-2(3-->20)abeo-taxa-4(20),11-diene-9,10-dione (1)] and dantaxusin B [5 alpha-cinnamoyloxy-9 alpha-hydroxy-10 beta,13 alpha-diacetoxytaxa-4(20),11-diene (2)], were isolated from an ethanol extract of the aerial parts of Taxus yunnanensis along with taxuspine ...
Y, Shinozaki, N, Fukamiya, M, Fukushima, M, Okano, T, Nehira, K, Tagahara, S X, Zhang, D C, Zhang, K H, Lee   +8 more
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A New Taxane Diterpene from Taxus yunnanensis

Journal of Natural Products, 1996
A new 11(15→1)-abeotaxane diterpene, 7,9-dideacetyltaxayuntin (1), and 11 known taxane diterpenes were isolated from the bark of Taxus yunnanensis. Their structures were determined primarily on the basis of analysis of their 1 H NMR, 13 C NMR, DEFT, 1 H- 1 H COSY, HMQC, HMBC, and mass spectra.
Shi-Zhou Zhong, Zhen-Xin Hua, Jing-Song Fan   +2 more
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[Studies on the chemical constituents of Taxus yunnanensis].

Yao xue xue bao = Acta pharmaceutica Sinica, 1992
The ethanolic extract of the bark of Taxus yunnanensis Cheng et L. K. Fu. showed significant antineoplastic effect on the transplantable tumors in mice. The life survival of P388 leukemic bearing mice was increased (84%) and the growth of B16 melanoma in mice was inhibited (53%).
W M, Chen, P L, Zhang, B, Wu, Q T, Zheng
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Three New Taxanes from the Roots of Taxus yunnanensis

Chemistry Letters, 1994
Abstract Three new taxane type diterpenoids, taxuyunnanine B, C and D were isolated together with the known taxusin, 2α-deacetoxytaxinine J and taxinine J from the roots of Taxus yunnanensis and their structures were elucidated by spectroscopic means.
Honjie Zhang, Yoshio Takeda, Yoshinori Minami, Kenichiro Yoshida, Takashi Matsumoto, Wei Xiang, Oing Mu, Handong Sun   +7 more
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Structural characterization and in vitro antitumor activity of a novel polysaccharide from Taxus yunnanensis

Carbohydrate Polymers, 2013
The shrub, Taxus yunnanensis is famed as the source of the important anticancer drug, paclitaxel. But research on its polysaccharides contents has been scarce. The present research aimed to investigate the polysaccharide content of T. yunnanensis leaves and study the antitumor activities of isolated polysaccharide(s) using human tumor cells (K-562 and ...
Chunyan, Yan, Yin, Yin, Dawei, Zhang, Wei, Yang, Rongmin, Yu   +4 more
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In vivo anti-osteoporotic activity of isotaxiresinol, a lignan from wood of Taxus yunnanensis

Phytomedicine, 2006
Isotaxiresinol, the main lignan isolated from the water extract of wood of Taxus yunnanensis, was investigated for its effect on bone loss, on serum biochemical markers for bone remodeling and on uterine tissue, using ovariectomized (OVX) rats as the model of postmenopausal osteoporosis.
J, Yin, Y, Tezuka, , Subehan, L, Shi, M, Nobukawa, T, Nobukawa, S, Kadota   +6 more
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Dantaxusins C and D, Two Novel Taxoids from Taxus yunnanensis

Journal of Natural Products, 2002
Two new taxane diterpenes, dantaxusin C (1) and dantaxusin D (2), were isolated from an ethanol extract of the aerial parts of Taxus yunnanensis along with 14 known taxoids. All structures were established on the basis of 1D and 2D NMR and HREIMS spectroscopic methods.
Youichi, Shinozaki, Narihiko, Fukamiya, Masao, Fukushima, Masayoshi, Okano, Tatsuo, Nehira, Kiyoshi, Tagahara, Shun-Xiang, Zhang, De-Cheng, Zhang, Kuo-Hsiung, Lee   +8 more
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Yunantaxusin A, a New 11(15→1)-abeo-Taxane from Taxus yunnanensis

Journal of Natural Products, 1994
Yunantaxusin A [2], an 11(15-->1)abeo-taxane-type diterpene with an opened oxetane ring, has been isolated from the leaves and stems of Taxus yunnanensis. Its structure was established from its spectral data.
S, Zhang, C, Tung-Ling Lee, Y, Kashiwada, K, Chen, D C, Zhang, K H, Lee   +5 more
openaire   +2 more sources