Results 51 to 60 of about 2,534 (156)

Efficacy and Tolerability of Topical Trifarotene in Managing Acne Vulgaris Among Malaysians: A Single Arm, Open Label, Observational Study

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Trifarotene is a new fourth‐generation topical retinoid that selectively binds to RAR‐γ receptors. However, the efficacy and safety data of trifarotene on Asians are lacking. Thus, we evaluated its real‐world efficacy and tolerability among Malaysians.
Jun Hui Goh, Tatt Quan Tan, Wen Chung Ho, Chi Fai Lee, Meroshini Sundaran, JiaXu An, Kang Nien How   +6 more
wiley   +1 more source

Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective

JEADV Clinical Practice, Volume 5, Issue 2, Page 394-401, June 2026.
ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto, Victoria Griffith, Samuel Stahly, Jere Mammino   +3 more
wiley   +1 more source

Tazarotene 0.045% Lotion for Moderate-to-Severe Acne in Male and Female Participants: A Phase II Post-hoc Analysis

, 2021
BACKGROUND: In a Phase II study, tazarotene 0.045% lotion was statistically superior to vehicle and comparable to tazarotene 0.1% cream in reducing acne lesions, with fewer treatment-related adverse events (TEAEs) than the cream.
Baldwin, Hilary E., Guenin, Eric Pierre, Green, Lawrence J., Kircik, Leon, Loncaric Forest, Anya, Pillai, Radhakrishnan   +5 more
core   +1 more source

Efficacy and tolerability of 0.1% tazarotene cream and 0.05% tretinoin cream in the treatment of acne vulgaris

Bangabandhu Sheikh Mujib Medical University Journal, 2016
Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles that is seen primarily in adolescents. Objective: To compare the efficacy of 0.1 % tazarotene cream and 0.05% tretinoin cream in the treatment of mild to moderate
Mohammad Habibur Rahman, Md. Shahidullah Sikder, Lubna Khondker   +2 more
doaj   +1 more source

Recent Advances in Nickel Catalysts for Sonogashira Coupling

ChemistryOpen, Volume 15, Issue 5, May 2026.
The Sonogashira coupling, catalyzed by transition metals, has become a valuable method for forming carbon‐carbon bonds. Nickel has gained considerable interest due to its lower cost and more environmentally friendly profile compared to palladium.
Sara Payamifar, Pegah Etminan, Ahmad Poursattar Marjani   +2 more
wiley   +1 more source

The Multifaceted Role of Keratinocytes in Hidradenitis Suppurativa Pathogenesis

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disorder of the pilosebaceous unit, with multiple factors contributing to its onset, activity and progression. Alongside a predisposing genetic background, hormonal and microbiome alterations, dysregulation of innate and adaptive immune response, as well as environmental ...
Chiara Moltrasio, Angelo Valerio Marzano, Maurizio Romagnuolo   +2 more
wiley   +1 more source

Evidence of increased apoptosis and reduced proliferation in basal cell carcinomas treated with tazarotene [PDF]

, 2004
A preliminary clinical experience suggested tazarotene, a new acetylenic retinoid, as an effective alternative topical treatment of basal cell carcinomas (BCC). The mechanisms of action of this synthetic retinoid, however, have not been yet clarified. In
Bianchi, L, Costanzo, Antonio, Spagnoli, Luigi Giusto, Orlandi, A, Chimenti, S, Campione, Elena, Campione, E, Costanzo, A, Orlandi, Augusto, Bianchi, Luca, Spagnoli, LG, Chimenti, Sergio   +11 more
core   +1 more source

Rational Formulation Design of Topical Tazarotene a Third-Generation Retinoid [PDF]

The skin acts as an essential barrier to the outside world through a complex structure of lipids and proteins making topical drug delivery a major challenge for formulation scientists.
Sherif, Solomon
core   +1 more source

Efficacy and Tolerability of a Triple Acid‐Containing Serum Combined With 0.1% Adapalene in Mild‐to‐Moderate Acne Vulgaris: A Randomized, Open‐Label Controlled Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Although topical retinoids are first‐line therapy for mild‐to‐moderate acne, treatment‐related irritation often limits adherence to long‐term therapy. However, dermocosmetic adjuncts may improve treatment outcomes and tolerability.
Jing LYu, Jiajia Li, Yang Jiang, Sha Wang, Qingchun Diao   +4 more
wiley   +1 more source

The p73 gene is an anti-tumoral target of the RAR beta/gamma-selective retinoid tazarotene [PDF]

, 2004
Tazarotene, a member of the new class of acetylenic retinoids, has been shown to be effective in the treatment of several hyperproliferative skin diseases, including non-melanoma skin cancer.
Papoutsaki, M, Marinari, Barbara, Papoutsaki, Marina, Marinari, B, Francesca Moretti, Sergio Chimenti, Chimenti, S, LEVRERO, Massimo, Marina Papoutsaki, Costanzo, A, Nisticò, Steven, Mauro Lanza, Chimenti, Sergio, Lanza, Mauro, NISTICO', STEVEN PAUL, Costanzo, Antonio, Lanza, M, Steven Nistico, Moretti, Francesca, Nistico, S, Barbara Marinari, Antonio Costanzo, Moretti, F, Levrero, M   +23 more
core   +1 more source