Results 51 to 60 of about 658,776 (286)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

İlkokul 3. ve 4. Sınıf Öğrencilerine Yönelik Matematik Kaygı Ölçeğinin Psikometrik Özelliklerinin İncelenmesi

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi, 2023
Bu araştırmanın amacı, ilkokulda öğrenim görmekte olan öğrencilerin matematik kaygı düzeylerini ölçmek için Mutlu ve Söylemez (2018) tarafından geliştirilmiş testin psikometrik özelliklerini Rasch Ölçme Teorisi çerçevesinde incelemektir.
Samet Yavuz Terzi   +2 more
doaj   +1 more source

TC-derived soluble mediators induced neutrophil chemotaxis.

open access: yes, 2018
A. Neutrophil chemotaxis toward TC-CM or the control medium was evaluated using 3 μm cell culture inserts in 96-well companion plates. Neutrophils (2.5 × 106 cells/ml per 75 μl) were allowed to migrate (37°C, 60 minutes) toward a TC-CM or the control ...
Raffaella Iannone (5464451)   +12 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

BIOCHEMICAL CHANGES AND ENDOCRINE RESPONSES IN PRE-COMPETITION TRAINING IN ELITE SWIMMERS

open access: yesBiology of Sport, 2012
The aim of this study was to describe biochemical changes and endocrine responses to low-volume pre-competition swimming training for elite swimmers. Twelve sprint swimmers (6 males and 6 females) participated in 3-week pre-competition training. Measures
Yue Li   +4 more
doaj  

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Effect of Various Intensities of Circuit Resistance Training on Plasma Levels of High-Density Lipoprotein-Associated Apolipoprotein O, Total Cholesterol and Triglyceride in Untrained Men

open access: yesMedical Laboratory Journal, 2019
Background and Objectives: Apolipoprotein O (apoO) is a 198 amino acids protein that exists predominantly in high-density lipoprotein (HDL). It may exert cardioprotective effects via decreasing fat accumulation and increasing removal of cholesterol from ...
Abbass Ghanbari Niaki   +4 more
doaj  

Sustainability of lemon (Citrus aurantifolia Swingle) farms in the province of Santa Elena, Ecuador

open access: yesPeruvian Journal of Agronomy, 2018
Se aplicaron encuestas a una muestra de 83 productores de limón de esta provincia, con preguntas estructuradas sobre dimensiones económicas, ecológicas y socioculturales.
M. Santistevan   +5 more
doaj   +1 more source

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