Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Layered superconductors as negative-refractive-index metamaterials
We analyze the use of layered superconductors as anisotropic metamaterials. Layered superconductors can have a negative refraction index in a wide frequency range for arbitrary incident angles.
A. L. Rakhmanov +5 more
core +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Pressure-induced electronic topological transitions in low dimensional superconductors
In the high-Tc cuprates, the unusual dependence of Tc on external pressure results from the combination of the nonmonotonic dependence of Tc on hole doping or hole-doping distribution among inequivalent layers, and from an ``intrinsic'' contribution ...
Angilella, G. G. N.
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Teacher perceived emotional job demands scale: Validity, reliability and invariance study
The aim of this study was to develop a measurement tool to determine teachers' perceived emotional job demands. The item pool created as a result of a literature review conducted by researchers was subjected to expert evaluation for content, appearance ...
Yılmaz Arslan +4 more
doaj +1 more source
Disparity of superconducting and pseudogap scales in low-Tc Bi-2201 cuprates
We experimentally study transport and intrinsic tunneling characteristics of a single-layer cuprate Bi(2+x)Sr(2-y)CuO(6+delta) with a low superconducting critical temperature Tc < 4 K.
A. I. Larkin +10 more
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Phase fluctuations and the pseudogap in YBa2Cu3Ox
The thermodynamics of the superconducting transition is studied as a function of doping using high-resolution expansivity data of YBa2Cu3Ox single crystals and Monte-Carlo simulations of the anisotropic 3D-XY model. We directly show that Tc of underdoped
A. B. Pippard +36 more
core +1 more source

