Results 181 to 190 of about 2,037,833 (287)

Glutamine-driven reductive TCA cycle metabolism supports aged muscle stem cell function via de novo lipogenesis. [PDF]

Nat Aging
Lee DE, McKay LK, Bareja A, Yang J, He W, Hill DA, Bain JR, Kuang S, Zhang GF, Newgard CB, White JP.   +10 more
europepmc   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source

Metabolic modulation of TCA cycle by <i>S</i>-nitrosylation in <i>Monascus</i> spp. [PDF]

Synth Syst Biotechnol
Meng Z, Tan Y, Duan Y, Li M.
europepmc   +1 more source

Quantitative Partitioning of Photoautotrophic and Photoheterotrophic Contributions During Mixotrophic Growth of Scenedesmus obliquus

Biotechnology and Bioengineering, EarlyView.
Carbon and oxygen fluxes during photoautotrophic, photoheterotrophic and mixotrophic growth of Scenedesmus obliquus. ABSTRACT Mixotrophic growth of microalgae involves the simultaneous assimilation of inorganic and organic carbon sources, but the quantitative contributions of photoautotrophic and photoheterotrophic metabolisms remain poorly resolved ...
Solène Jahan, Thibault Combroux, Samy Kemel, Hélène Marec, Mariana Titica, Howard Fallowfield, Jérémy Pruvost, Guillaume Cogne   +7 more
wiley   +1 more source

TCA cycle-derived oncometabolites in cancer and the immune microenvironment. [PDF]

J Biomed Sci
Sarkar S, Chang CI, Jean J, Wu MJ.
europepmc   +1 more source

Autonomous Control of Gene Expression Using Endogenous Transcription Signals

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Autonomous cell‐based control of heterologous gene expression can simplify batch‐culture bioprocessing by eliminating external monitoring and extrinsic control of culture conditions. Existing approaches use auto‐induction media, synthetic cell‐cell communication systems, or application‐specific biosensors.
Pakpoom Subsoontorn, Drew Endy, Olivier Borkowski   +2 more
wiley   +1 more source

TCA-cycle metabolites in the nucleus: drivers of chromatin and epigenetic control. [PDF]

BMC Biol
Ghisletti S, Russo M.
europepmc   +1 more source

From apex to base: Uncovering spatial metabolic adaptation in Antarctic mosses

Bulletin of the Korean Chemical Society, EarlyView.
Antarctic mosses survive extreme cold, desiccation, UV exposure, and oxidative stress. We analyzed three species by separating apical, middle, and basal zones. Each zone showed distinct metabolite patterns and biological roles, revealing spatial metabolic specialization. The results suggest that whole‐plant survival depends on coordinated contributions
Fatima Tuz Zahra, Yelim Lee, Hyoungseok Lee, Amancio de Souza, Manhoi Hur, Katayoon Dehesh, Jungeun Lee, Sunghwan Kim   +7 more
wiley   +1 more source

Vespakinin-M delineates an AMPK/mTOR-arginine-TCA cycle axis to act as an immunometabolic switch in post-stroke microglia. [PDF]

Redox Biol
Wang D, Zhang J, Zhuang Z, Wang Q, Li J, Wang X, Li K, Liu Y, Cao Y, Li L, Zhang Y, Zhao Y, Zhao Y, Zhao H, Zhang C.   +14 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source