Results 51 to 60 of about 2,037,833 (287)
TCA cycle gene present in ANME archaea.
, 2022 (A) Schematic of the enzymes and reactants in the partial oxidative and reductive TCA cycles in ANME that lead to 2-oxoglutarate for the purpose of producing anabolic intermediates for biosynthesis.
Danielle Goudeau (8455311) +16 more
core +1 more source
The Tricarboxylic Acid Cycle Metabolites for Cancer: Friend or Enemy
ResearchThe tricarboxylic acid (TCA) cycle is capable of providing sufficient energy for the physiological activities under aerobic conditions. Although tumor metabolic reprogramming places aerobic glycolysis in a dominant position, the TCA cycle remains ...
Jie Wu +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Protocole de traitement des TCA en Corse
, 2021 Un protocole pour le traitement des TCA, élaboré originellement à l'attention des archéologues du centre Inrap de Vescovato en Corse, est accompagné d'une fiche d'enregistrement de terrain établie pour les tuiles de couverture.
Étienne Jaffrot
core
Area under the curve for anaplerotic and TCA cycle fluxes.
, 2023 Area under the curve for anaplerotic and TCA cycle fluxes.
Christina A. Pacak (16914168) +7 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu +10 more
wiley +1 more source
Quantitative analysis of the physiological contributions of glucose to the TCA cycle [PDF]
Cell Metabolism, 2019 ABSTRACT The carbon source for catabolism in vivo is a fundamental question in metabolic physiology. Limited by data and rigorous mathematical analysis, controversy exists over the nutritional sources for carbon in the tricarboxylic acid (TCA) cycle under physiological settings ...
Liu, Shiyu +4 more
openaire +2 more sources
Expression of TCA cycle-related proteins.
, 2014 (A) NC, (B) LV-shRNA+5 mM lysine (GA1 model cells), (C) NC+5 mM lysine, (D) LV-shRNA, (E) GA1 model cells +10 mM leucine, (F) GA1 model cells +0.45 g/L tyrosine, (G) GA1 model cells+2 mM arginine, (H) GA1 model cells +2 mM homoarginine, (I) GA1 model ...
Jinzhi Gao (409608) +7 more
core +1 more source