Results 71 to 80 of about 13,392 (209)

Combination effects of nano-TiO2 and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on biotransformation gene expression in the liver of European sea bass Dicentrarchus labrax

, 2015
The aim of present study was to investigate the influence of titanium dioxide nanoparticles (nano-TiO2, Aeroxide® P25) on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dependent biotransformation gene expression in liver of juvenile European sea bass ...
Leaver, Michael J., Grassi, Giacomo, Corsi, Ilaria, Vannuccini, Maria Luisa, Leaver, Michael   +4 more
core   +1 more source

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the differentiation of embryonic stem cells towards pancreatic lineage and pancreatic beta cell function

Environment International, 2019
Animal and epidemiological studies demonstrated association of persistent exposure of TCDD, an endocrine disrupting chemical, to susceptibility of type 2 diabetes (T2D).
John A. Kubi, Andy C.H. Chen, Sze Wan Fong, Keng Po Lai, Chris K.C. Wong, William S.B. Yeung, Kai Fai Lee, Yin Lau Lee   +7 more
doaj   +1 more source

NAC inhibited TCDD-induced senescence in PC12 neuronal cells.

, 2014
(A) PC12 cells were pre-treated with DMSO, 50 nM TCDD, or 50 nM TCDD plus 5 mM NAC for 72 h before SA-β-Gal staining was performed.
Lingwei Liang (526592), Jiao Liu (135688), Songlin Zhou (205503), Zhiqing Duan (526590), Cuiying Tang (526591), Chunhua Wan (163677), Xiaoke Nie (526588), Jianya Zhao (526589), Guangfei Xu (323382)   +8 more
core   +1 more source

Derivation and internal validation of the multivariate toxigenic C. difficile diarrhea model and risk score for emergency room and hospitalized patients with diarrhea

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Many factors have been associated with the risk of toxigenic C. difficile diarrhea (TCdD). This study derived and internally validated a multivariate model for estimating the risk of TCdD in patients with diarrhea using readily available ...
Sarah Davies, Jimmy Zhang, Yongjun Yi, Eric R. Burge, Marc Desjardins, Peter C. Austin, Carl van Walraven   +6 more
doaj   +1 more source

Tissue-specific induction of EROD activity and CYP1A protein in Sparus aurata exposed to B(a)P and TCDD

, 2007
The purpose of this study was to compare xenobiotic CYP1A induction in liver, gills, and excretory kidney of gilthead seabream, Sparus aurata. Fishes were exposed via water for 20 days to different concentrations of benzo(a)pyrene (B(a)P) or 2,3,7,8 ...
Segner, Helmut, Ortiz-Delgado, J B, Behrens, Arno, Sarasquete, Carmen, Behrens, A, Ortiz-Delgado, Juan B., Segner, H, Sarasquete, C   +7 more
core   +1 more source

Indole-3-Carbinol Enhances Alternative Activation of Macrophages via AHR Pathway and Glucose Transporter Regulation

Immuno
Disruption in macrophage polarization is linked to inflammatory diseases and metabolic disorders. Our study aimed to investigate how AHR activation by I3C and TCDD could impact glucose transporters and macrophage phenotypes and functions in human ...
Delara Omrani, Saeed Mohammadi, Moein Malekzadeh, Mohsen Saeidi, Fakhri Sadat Seyedhosseini, Ahmed Al-Harrasi, Yaghoub Yazdani   +6 more
doaj   +1 more source

TCDD effect on MDBK cells viability during BHV-1 infection.

, 2013
Cell viability evaluated by an MTT assay procedure on MDBK cultures incubated or not with different TCDD concentrations (0.01, 1, 100 pg/ml) for various times post-BHV-1 infection (12, 24 and 48 hours p.i.) at a MOI of 1, as indicated in the legends ...
Carlo Irace (387397), Alfredo Colonna (387399), Rita Santamaria (387400), Luisa De Martino (339970), Giuseppe Iovane (339969), Antonio Di Pascale (387398), Filomena Fiorito (339966), Ugo Pagnini (339967)   +7 more
core   +1 more source

Proteomic changes of aryl hydrocarbon receptor (AhR)-silenced porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

PLoS ONE, 2019
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a toxic man-made chemical compound contaminating the environment and affecting human/animal health and reproduction. Intracellular TCDD action usually involves the activation of aryl hydrocarbon receptor (AhR)
Karina Orlowska, Sylwia Swigonska, Agnieszka Sadowska, Monika Ruszkowska, Anna Nynca, Tomasz Molcan, Agata Zmijewska, Renata E Ciereszko   +7 more
doaj   +1 more source

The Effects of Benzo(a)pyrene and 2, 3, 7, 8-Tetrachlorodibenzo-p-diox:in from Automobile Exhaust...

Promet (Zagreb), 2012
Incomplete combustion process is a potential source ofbenzo(a)pyrene (BaP) and tetrachlorodibenzo-p-dioxin(TCDD ). These compounds have been detected in effluents ofmunicipal incinerators, sewage sludge, cigarette smoke, automobileexhaust etc.
Olga Carević
doaj   +1 more source

TCDD exposure-response analysis and risk assessment

, 2006
We examined the relation between cancer mortality and time-dependent cumulative exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) estimated from a concentration- and age-dependent kinetic model of elimination, and we estimated incremental cancer ...
Aylward, Lesa, Cheng, Hong, Starr, Thomas B., Carrier, Gaetan, Brunet, Robert C., Delzell, Elizabeth, Beall, Colleen   +6 more
core   +1 more source