Results 61 to 70 of about 13,392 (209)

The growth and infectivity of Leishmania major is not altered by in vitro exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

BMC Research Notes, 2018
Objective The numbers of Leishmania major parasites in foot lesions of C57Bl/6, BALB/c or SCID mice can be significantly reduced by pre-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). One potential mechanism to explain this enhanced resistance to
Vera Sazhnev, Gregory K. DeKrey
doaj   +1 more source

Modifying Effect of the Antibiotic Action, Membrane Permeability, and ADMET/Toxicity Profile of the Fixed Oil From the Pulp of Mauritia Flexuosa F.L. (Arecaceae)

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT The increasing bacterial resistance to antibiotics has stimulated the search for natural products capable of modulating antimicrobial activity. In this study, the fixed oil from Mauritia flexuosa pulp was evaluated for its antibacterial activity, modulatory effect on antibiotics, membrane permeability, and ADMET/toxicity profile.
Isaac Moura Araújo, Cleidiana Tomé de Oliveira, Luís Pereira‐de‐Morais, Andressa Silva Alencar, Cicera Datiane de Morais Oliveira‐Tintino, Maria Alícia Cavalcante Narciso, Anita Oliveira Brito Pereira Bezerra Martins, Sara Tavares de Sousa Machado, Sheila Alves Gonçalves, Daniel Sampaio Alves, Janaina Esmeraldo Rocha, Ana Carolina Ferreira Araújo, Priscilla Ramos Freitas, José Weverton Almeida‐Bezerra, José Thyálisson da Costa Silva, Henrique Douglas Melo Coutinho   +15 more
wiley   +1 more source

Potential AhR-independent mechanisms of 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibition of human glioblastoma A172 cells migration

Ecotoxicology and Environmental Safety
The toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is generally believed to be mediated by aryl hydrocarbon receptor (AhR), but some evidence suggests that the effects of TCDD can also be produced through AhR-independent mechanisms.
Yiyun Liu, Ruihong Zhu, Tuan Xu, Yangsheng Chen, Yuan Ding, Sijia Zuo, Li Xu, Heidi Qunhui Xie, Bin Zhao   +8 more
doaj   +1 more source

Rapid transformation of 1,2,3,4-TCDD by Pd/Fe catalysts

, 2010
This study investigated reductive dechlorination of 1,2,3,4-tetrachlorodibenzo-p-dioxin (1,2,3,4-TCDD) in the presence of Pd/Fe, Cu/Fe and Ni/Fe bimetallic catalysts or zero-valent iron (ZVI) under aqueous and ambient temperature conditions. It was found
Wang, ZY, Wang, Zhiyuan, Fennell, DE, Peng, PA, Huang, WL, Huang, Weilin, Peng, Ping'an, Fennell, Donna E.   +7 more
core  

RETRACTED: 2, 3, 7, 8-Tetrachlorodibenzo-P-dioxin (TCDD) induces premature senescence in human and rodent neuronal cells via ROS-dependent mechanisms.

PLoS ONE, 2014
The widespread environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a potent toxicant that causes significant neurotoxicity. However, the biological events that participate in this process remain largely elusive. In the present study, we
Chunhua Wan, Jiao Liu, Xiaoke Nie, Jianya Zhao, Songlin Zhou, Zhiqing Duan, Cuiying Tang, Lingwei Liang, Guangfei Xu   +8 more
doaj   +1 more source

Reduced Gluconeogenesis in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-treated Rats.

, 1990
The effect of a usually lethal dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 125 μg/kg) was studied on the conversion of14C-alanine into14C-glucose in male Sprague-Dawley rats by established procedures (determination of plasma alanine and blood ...
Weber, L.W.D., Rozman, K.K., Gorski, J.R.   +2 more
core   +1 more source

Altered Sex Ratio at Birth with Maternal Exposure to Dioxins in Vietnamese Infants

Toxics
Excess female births (lower sex ratio at birth) associated with paternal exposure to 2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD) have been reported in Italy. However, no significant effects of maternal TCDD exposure on the sex ratio were reported.
Noriko Kaneko, Muneko Nishijo, Hoa Thi Vu, Tai Pham-The, Thao Ngoc Pham, Nghi Ngoc Tran, Tomoya Takiguchi, Yoshikazu Nishino   +7 more
doaj   +1 more source

Organ-specific effects on glycolysis by the dioxin-activated aryl hydrocarbon receptor.

PLoS ONE, 2020
Activation of the aryl hydrocarbon receptor (AHR) by the environmental toxin dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD) causes diverse toxicities, including thymus atrophy and hepatosteatosis.
Silvia Diani-Moore, Tiago Marques Pedro, Arleen B Rifkind   +2 more
doaj   +1 more source

Elucidating Transcription Factor Regulation by TCDD within the HS1,2 Enhancer [PDF]

, 2012
Immunoglobulin heavy chain (IgH) expression and Ig secretion is inhibited by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD).
Ochs, Sharon D.
core   +2 more sources

Microsomal Ferritin Iron Release in Relation to TCDD Toxicity [PDF]

, 1983
Previous experiments have demonstrated that the hepatoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) involves synergism with iron. It has been postulated that it is storage iron that plays a role in toxic effects observed with TCDD poisoning.
Rowley, R.
core   +1 more source