Results 41 to 50 of about 13,392 (209)
2,3,7,8-Tetrachlorodibenzo-p-dioxin and -Mediated Mouse Embryonic Palatal Mesenchymal Cells
Dose-Response, 2019 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a well-known environmental teratogenic effector for cleft palate. Transforming growth factor 3 ( TGF-β3 ) is an essential growth factor for palatogenesis. The objective of this study is to clarify the effects
Liyun Gao +5 more
doaj +1 more source
TCDD dysregulation of 13 AHR-target genes in rat liver [PDF]
, 2014 Despite several decades of research, the complete mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other xenobiotic agonists of the aryl hydrocarbon receptor (AHR) cause toxicity remains unclear.
Okey, Allan B. +5 more
core +1 more source
Antioxidants, 2021 Exposure to environmental chemicals during pregnancy and lactation is a contributing factor in gut microbiota dysbiosis and linked to programming of hypertension. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic dioxin, induces toxic effects by
Chien-Ning Hsu +4 more
doaj +1 more source
3D Liver Fibrosis Models in Lab: A Novel Modality for Drug Screening
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT Liver fibrosis is the common consequence of liver injury caused by a variety of chronic liver disorders. This condition leads to the development of more severe complications, particularly cirrhosis and hepatocellular carcinoma. Despite abundant studies, the fundamental cell and molecular mechanisms of liver fibrosis are still unknown.
Hani Keshavarz Alikhani +10 more
wiley +1 more source
Melatonin as a protector against endocrine disruption across tissues: A systematic review
Physiological Reports, Volume 14, Issue 15, August 2026.Graphical Abstract showing the biological mechanisms by which melatonin protects tissues against endocrine disruption. Abstract Endocrine‐disrupting chemicals (EDCs) are widespread environmental pollutants that interfere with hormonal homeostasis and contribute to multisystem toxicity.
Clenie Isingizwe +2 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 7, July 2026.Pre‐operative and post‐operative T2 MRI and PSMA PETCT. ABSTRACT Prostate cancer is the most commonly diagnosed cancer and the second leading cause of cancer death in men. Acinar adenocarcinoma accounts for 90% of primary prostatic cancers. Carcinoma of the basal cells of the prostate is extremely rare, making up less than 1% of prostate cancer ...
German Santiago Herrera Alzate +5 more
wiley +1 more source
Update of the risk assessment on emerging and novel brominated flame retardants in food
EFSA Journal, Volume 24, Issue 7, July 2026.Abstract The European Commission asked EFSA to update its 2012 risk assessment on Emerging and Novel brominated flame retardants (BFRs) in food. Since the previous Opinion, further information was collected for a total of 27 BFRs. The CONTAM Panel concluded that TDBPP, DBPNG and TBNPA are considered genotoxic and carcinogenic.
EFSA Panel on Contaminants in the Food Chain (CONTAM) +33 more
wiley +1 more source
, 2019 Fetal rat exposure to TCDD reduces epididymal sperm number and a proposed mode-of-action (MOA) involves altered pituitary-testicular hormonal signaling.
Johnson, K (via Mendeley Data)
core +1 more source
Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.Vitamin D receptor (VDR) signaling is implicated in inflammatory senescence‐associated skin aging, a growing health concern in aging populations where cellular senescence and chronic inflammation converge to create complex pathophysiological conditions.
Liancheng Guan +8 more
wiley +1 more source