Results 51 to 60 of about 12,887,061 (145)

Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.

, 2007
BACKGROUND & AIMS: Aberrant activation of the beta-catenin/Tcf-4 transcriptional complex represents an initiating event for colorectal carcinogenesis, shifting the balance from differentiation toward proliferation in colonic crypts.
Philippe Jay, Frédéric Hollande, Yim, Mildred, Christine Pignodel, Baldwin, Graham S, Jessica Coelho, Delaunay, Nathalie, Nathalie Delaunay, Arthur Shulkes, Stéphanie Boireau, Pélegrin, André, Pignodel, Christine, Mildred Yim, Ryan, Joanne, Boireau, Stéphanie, Gérard Lambeau, Pannequin, Julie, Hollande, Frédéric, Joanne Ryan, Jean–François Bourgaux, André Pélegrin, Shulkes, Arthur, Joubert, Dominique, Fanny Surrel, Bourgaux, Jean-François, Jay, Philippe, Surrel, Fanny, Coelho, Jessica, Julie Pannequin, Michael Buchert, Graham S. Baldwin, Buchert, Michael, Pomila Singh, Singh, Pomila, Dominique Joubert, Lambeau, Gérard   +35 more
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The inhibitory mechanism of curcumin and its derivative against β-catenin/Tcf signaling [PDF]

, 2005
We investigated the inhibitory mechanism of curcumin and its derivative (CHC007) against β-catenin/T-cell factor (Tcf) signaling in various cancer cell lines.
Hahm, Eun Ryeong, Kim, Hyun-Kyung, Eun Ryeong Hahm, Park, Seyeon, Yang, Chul Hak, Chul Hak Yang, Chi Hoon Park, Park, Chi Hoon, Seyeon Park, Hyun-Kyung Kim   +9 more
core   +1 more source

Review of TCF Assistance [PDF]

The Commission was asked to evaluate current assistance arrangements to the TCF industries and provide policy options for post 2005 assistance and to report on a range of related matters that will affect the sector's long-term viability. The inquiry will
Productivity Commission
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Targeting Wnt/β-Catenin Activated Cells with Dominant-Negative N-cadherin to Reduce Neointima Formation

Molecular Therapy: Methods & Clinical Development, 2017
Approximately 50% of coronary artery bypass grafts using the autologous saphenous vein fail within 10 years due to intimal thickening. This study examined whether a gene therapy approach that selectively kills Wnt/β-catenin/T cell factor (TCF) activated ...
Sarah Hulin-Curtis, Helen Williams, Kerry S. Wadey, Graciela B. Sala-Newby, Sarah J. George   +4 more
doaj   +1 more source

Binding of TCF-4 and β-catenin to the proximal FasL TCF/LEF-1 binding element (TBE2).

, 2013
A). Radio-labeled wild-type TBE2 probe (-205C allele, lane 1-6) and mutant TBE2 probe (-205G allele) (lane 6) were incubated with 8 µg of SW480 cell nuclear extracts for 30 min.
Rui Lin (219434), Fenglong Xie (342385), Jinhai Huang (132142), Robert P. Kimberly (139689), Maureen H. Richards (342380), Lena Al-Harthi (342381), Andrew W. Gibson (342387), Jeffrey C. Edberg (219565), Xiulong Xu (342383), Jianming Wu (312135)   +9 more
core   +1 more source

Molecular control of adipogenesis: Regulation by TCF -4N and Frizzleds.

, 2005
Wnts are secreted proteins that play important roles in many aspects of cell fate. Our lab has previously demonstrated that canonical Writ signaling inhibits preadipocyte differentiation. Writs act through Frizzled receptors to activate several signaling
Kennell, Jennifer Arianne
core   +5 more sources

Transactivation of MCP-1/CCL2 by beta-catenin/TCF-4 in human breast cancer cells [PDF]

, 2006
peer reviewedThe loss of E-cadherin expression and the translocation of beta-catenin to the nucleus are frequently associated with the metastatic conversion of epithelial cells. In the nucleus, beta-catenin binds to the TCF/LEF-1 (T-cell factor/ lymphoid
Buttice, G., Polette, Myriam, C., Buttice, G, Buttice, Giovanna, Ueda, A., Foidart, Jean-Michel, Ueda, Atsuhisa, Mestdagt, M, Polette, M., Gilles, Christine, Noël, Agnès, Ueda, A, Polette, M, Mestdagt, Mélanie   +13 more
core   +1 more source

Transfection of Axin Gene Down-regulates Expressions of β-catenin and TCF-4 and Inhibits the Proliferation and Invasive Ability of Lung Cancer Cells

Chinese Journal of Lung Cancer, 2009
Background and objective Axin is an important negative regulator of Wnt signaling pathway. It can induce the phosphorylation and degradation of β-catenin.
Shuli LIU, Hongtao XU, Lianhe YANG, Qingchang LI, Qiang WEI, Enhua WANG   +5 more
doaj  

Design and fashion in the Australian TCF industries

, 2008
The purpose of this report is to review the changing nature of the TCF industries and investigate the current state of play in the Australian fashion industry to determine potential strategies for future growth both nationally and globally.
Schmidt, Christine Margaret, Vaughan, Suzi   +1 more
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Review of Australia's general tariff arrrangements [PDF]

In 1999, the Commonwealth Government referred the scope for a post-2000 reduction in the general tariff to the Productivity Commission for inquiry and report within nine months. The general tariff covers only rates of 5 per cent or less, and excludes the
Productivity Commission
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