Cellular Physiology and Biochemistry, 2018 Background/Aims: Hyperglycemia is an important risk factor for the most severe cardiovascular diseases in patients with diabetes. It has been demonstrated that cardiac stem cells (CSCs) play a pivotal role in the maintenance of cardiac homeostasis and ...
Xiaoming Zhang +5 more
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Quantitative estimates of performance on the Taylor Complex Figure (TCF) by children aged 4-17 years [PDF]
Национальный психологический журнал, 2019 Introduction. The Taylor Complex Figure (TCF) technique is one of the neuropsychologist’s tools and is used to diagnose children after 4 y.o. and adults for assessing visual spatial characteristics, visual constructive skills and visual memory.
Nikita A. Khokhlov, Alexandra E. Serdyuk
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Wnt/β-catenin signaling pathway is a direct enhancer of thyroid transcription factor-1 in human papillary thyroid carcinoma cells. [PDF]
PLoS ONE, 2011 The Wnt/β-catenin signaling pathway is involved in the normal development of thyroid gland, but its disregulation provokes the appearance of several types of cancers, including papillary thyroid carcinomas (PTC) which are the most common thyroid tumours.
Marie Gilbert-Sirieix +6 more
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β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism [PDF]
, 2011 SummaryUnderstanding the mechanisms regulating pluripotency in embryonic and induced pluripotent stem cells is required to ensure their safe use in clinical applications.
Kelly, Kevin F. +11 more
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High Expression of TCF-4 Positively Correlated with Lung Cancer Progression
Chinese Journal of Lung Cancer, 2008 Background and objective TCF-4 is an important downstream molecule of Wnt signaling pathway, but studies on the expression level and significance of TCF-4 in lung cancer were still limited.
Enhua WANG +11 more
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Arquivos Brasileiros de Cardiologia, 2021 Resumo Fundamento A cardiopatia isquêmica atraiu muito atenção devido às altas taxas de mortalidade, custos do tratamento e a crescente morbidade na população jovem. Estratégias de reperfusão reduziram a mortalidade.
YuJiao Chen +5 more
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Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells [PDF]
, 2006 Swiss Cancer League, Swiss National Science Foundation and SNSF NCCR Molecular Oncology ProgrammeBackground: The Wnt signaling pathway is activated by mutations in the APC and beta-catenin genes in many types of human cancer.
Homicsko, Krisztian +19 more
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Systematic analysis of blood cell transcriptome in end-stage chronic respiratory diseases. [PDF]
PLoS ONE, 2014 BACKGROUND:End-stage chronic respiratory diseases (CRD) have systemic consequences, such as weight loss and susceptibility to infection. However the mechanisms of such dysfunctions are as yet poorly explained.
Julie Chesné +19 more
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Protein expression of TCF-4 isoforms J and K.
, 2012 (A) Organization of the “short” (A, B) and the “long” (J, K) isoforms; TCF-4B and J lack the SxxSS motif. (B) Confocal laser-scanning microscopy demonstrates nuclear localization of TCF-4J and TCF-4K (green). Nuclei are counterstained by DAPI.
Hironori Koga (23332) +8 more
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Tcf-4 knockdown suppresses Wnt signaling in colon cancer cells.
, 2013 SW480 and HCT116 cells were treated with adenoviruses (50 MOI) carrying shRNA. a, At 24 h post-infection, the cells were cotransfected with reporter genes harboring Tcf-4 binding sites (TOPflash) or a mutant Tcf-binding site (FOPflash), respectively ...
Xiao-Lei Wang (306055) +7 more
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