Results 101 to 110 of about 26,882 (189)

The role of the transcription factor Tcf-1 for the development and the function of NK cells [PDF]

, 2014
Natural Killer (NK) cells are innate immune cells that can eliminate malignant and foreign cells and that play an important role for the early control of viral and fungal infections. Further, they are important regulators of the adaptive and innate immune responses.
openaire  

Computational insights into β-catenin–tcf inhibition by bioactive compounds from Cucumis sativus for cancer treatment

Bulletin of the National Research Centre
Background The Wnt/β-catenin signaling pathway plays a vital role in embryogenesis, stem cell regulation, and tissue homeostasis. Aberrant activation of this pathway has been linked to the initiation and progression of various cancers.
Samson Marvellous Oladeji, Deborah Ngozi Conteh, Funmilayo Elizabeth Adeyemi, Timileyin Akinola Akintayo, Lukman Abidemi Bello, Damilola Comfort Ife-Bolade, Moses Akinwumi Akintunji, Festus Slade, Ridwan Oladimeji Ojo   +8 more
doaj   +1 more source

A gene family of HMG-box transcription factors with homology to TCF-1

Nucleic Acids Research, 1992
J, Castrop, K, van Norren, H, Clevers
openaire   +3 more sources

Control of Lymphocyte Differentiation by the LEF-1/TCF Family of Transcription Factors

Cold Spring Harbor Symposia on Quantitative Biology, 1999
T, Reya, R, Okamura, R, Grosschedl
openaire   +2 more sources

Differential Wnt/β-catenin signaling via TCF7L2/LEF1 binding specificity shapes cellular and tumor phenotypes. [PDF]

Proc Natl Acad Sci U S A
Kluiver TA, Nordin A, Lu Y, Guo X, Schubert SA, Yeung D, Ardisasmita AI, Terpstra W, Zhang C, Duan X, Savur R, van den Heuvel MC, de Meijer VE, de Kleine RH, Kraal K, de Krijger RR, Zsiros J, Cantù C, Peng WC.   +18 more
europepmc   +1 more source

Temporal neuronal differentiation programs safeguard neuronal diversity. [PDF]

Proc Natl Acad Sci U S A
Shen D, Chu J, Zhou X, Lan Z, Zhang R, Wang S, Tang H, Wang Y, Hu C, Li Z, Song Y.   +10 more
europepmc   +1 more source

WNT signaling : activation, repression and fine-tuning of TCF transcription factors

, 2003
In the absence of a Wnt signal ß-catenin is phosphorylated by GSK3-ß, in a complex also containing Axin and APC. Upon phosphorylation, ß-catenin is primed for ubiquitination and subsequent degradation by the proteasome. In the nucleus, Tcf proteins bind Groucho family members and repress target genes.
openaire   +1 more source

T Cell Exhaustion as a Regulated Differentiation Programme. [PDF]

Eur J Immunol
Veldhoen M, Ferreira C.
europepmc   +1 more source

Nur77 Is Associated With Polyfunctional Properties in Virus-Specific Human CD8⁺ T Cells. [PDF]

Eur J Immunol
Martel F, Rincón D, Passaes C, Arévalo L, Torres M, Ramirez N, Narváez CF, Toro JF, Sussmann O, Franco MA, Mateus J, Sidney J, Sette A, Sáez-Cirión A, Perdomo-Celis F.   +14 more
europepmc   +1 more source

The development of innate lymphoid cells. [PDF]

Nat Immunol
Das A, Ding Y, Harly C, Bhandoola A.
europepmc   +1 more source