Results 111 to 120 of about 197,260 (304)
Identification of lncRNA LINC02747 as a Novel Potential Biomarker for Breast Cancer [PDF]
Journal of Mazandaran University of Medical SciencesBackground and purpose: Breast cancer (BC) is the leading cause of cancer-related mortality among women worldwide. Consequently, the early identification of breast cancer is crucial for improving patient survival, and biomarkers represent promising tools
Mandana Kazemi +3 more
doaj
ICGC-TCGA-PanCancer/pcawg_delly_workflow: 2.0.2-cwl1.0
, 2019 <ul> <li>update in dockerfile</li> <li>documentation in CWL descriptor</li> </ul ...
lindaxiang +6 more
core +1 more source
Advanced Science, EarlyView.Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source
Racial disparities in hepatocellular carcinoma: a TCGA-based gene expression study of Caucasian and Asian populations [PDF]
Exploration of Targeted Anti-tumor TherapyAim: Hepatocellular carcinoma (HCC) displays both shared and ethnicity-specific molecular characteristics. Using transcriptomic data from The Cancer Genome Atlas (TCGA), we compared gene expression profiles between Asian and Caucasian HCC patients ...
Muhammad Rezki Rasyak +4 more
doaj +1 more source
Advanced Science, EarlyView.Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong +20 more
wiley +1 more source
Review The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge
Współczesna Onkologia, 2015 The Cancer Genome Atlas (TCGA) is a public funded project that aims to catalogue and discover major cancer-causing genomic alterations to create a comprehensive "atlas" of cancer genomic profiles. So far, TCGA researchers have analysed large cohorts of over 30 human tumours through large-scale genome sequencing and integrated multi-dimensional analyses.
Tomczak, Katarzyna +2 more
openaire +2 more sources
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
TCGADownloadHelper: simplifying TCGA data extraction and preprocessing
Frontiers in GeneticsThe Cancer Genome Atlas (TCGA) provides comprehensive genomic data across various cancer types. However, complex file naming conventions and the necessity of linking disparate data types to individual case IDs can be challenging for first-time users. While other tools have been introduced to facilitate TCGA data handling, they lack a straightforward ...
Alexandra Anke Baumann +6 more
openaire +3 more sources
TCGA-UCEC dataset and R package for constructing heatmap of Fig 1A.
TCGA-UCEC dataset and R package for constructing heatmap of Fig 1A.
Guang Wang (137916) +3 more
core +1 more source