Results 281 to 290 of about 272,710 (333)

Deep learning-driven TCR$$\beta$$ repertoire analysis enhances diagnosis and enables mining of immunological biomarkers in systemic lupus erythematosus [PDF]

open access: gold
Tongfei Shen   +9 more
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The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression. [PDF]

open access: yesNat Commun
Xu M   +24 more
europepmc   +1 more source

TCR β CDR3 repertoire remodeling in pediatric myocarditis reveals clonal expansion and disease-associated public clonotypes [PDF]

open access: gold
Xixiong Lin   +8 more
openalex   +1 more source

Data Sheet 1_Peripheral blood TCR repertoire improves early detection across multiple cancer types utilizing a cancer predictor.docx

open access: green
Yinglei Tang (22130068)   +4 more
openalex   +1 more source

Improvement of CD4, but not CD8, TCR BV repertoire after HAART

open access: green, 2000
Antonello Giovannetti   +7 more
openalex   +1 more source
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Selection influences naive CD8+ TCR‐β repertoire sharing

Immunology, 2021
SummaryWithin each individual, the adaptive immune system generates a repertoire of cells expressing receptors capable of recognizing diverse potential pathogens. The theoretical diversity of the T‐cell receptor (TCR) repertoire exceeds the actual size of the T‐cell population in an individual by several orders of magnitude – making the observation of ...
Hao H. Yiu   +4 more
openaire   +2 more sources

Insulin specific TCR repertoire analysis reveals functional diversity of Treg TCRs

The Journal of Immunology, 2022
Abstract Regulatory T cells (Tregs) are critical in preventing autoimmunity and express a unique TCR repertoire with high affinity to self-antigens. However, whether Treg and effector T cell (Teff) TCR repertoires are similarly divergent in the context of autoimmunity, and whether Tregs are able to maintain TCR affinity advantage has not
Yi Jing   +4 more
openaire   +1 more source

TCR repertoire in early fetal mouse thymus

International Immunology, 1995
We investigated the rearrangement and expression of TCR genes in mouse fetal thymus organ culture, a system that avoids subsequent entry of hematopoietic precursor cells. The first observable rearranged TCR gene was homogeneous V gamma 2-J gamma 2, detectable as early as fetal day 11 (d11) in the thymic primordia.
H, Ohki-Hamazaki   +5 more
openaire   +2 more sources

T Cell Receptor (TCR) Repertoire in Alloimmune Responses

International Reviews of Immunology, 1996
A large number of alloantigenic determinants could be generated by both the direct and indirect alloantigen presentation pathways. Hence, a heterogeneous population of T cells expressing a wide variety of receptors would be expected to respond to this diverse array of alloantigenic determinants.
O J, Finn, L A, Debruyne, D K, Bishop
openaire   +2 more sources

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