Results 161 to 170 of about 22,324 (258)

Isavuconazole in Pediatric Invasive Fungal Infections: Outcomes and Therapeutic Drug Monitoring in a Chinese Multicenter Case Series. [PDF]

Infect Drug Resist
Zou S, Shu C, Liang X, Liu C, Luo P, Chen Z, Xu D, Liu D, Zhang J, He Y.   +9 more
europepmc   +1 more source

Posters - Toxicology/TDM [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2006
openaire   +1 more source

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

MedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang, Ying Liu, Yilin Hou, Hongxia Niu   +3 more
wiley   +1 more source

Clinical Use of Bayesian Model-Informed Precision Dosing in Routine Practice: A Focused Systematic Review. [PDF]

J Clin Med
Alghamdi WA.
europepmc   +1 more source

Research hotspots and trends in therapeutic drug monitoring of anticancer drugs: a 1990-2024 bibliometric analysis. [PDF]

Front Oncol
Qian C, Yuan T, Lu G, He M, Li X, Su H, Li C.   +6 more
europepmc   +1 more source

Beyond Traditional Covariates: An Interpretable Machine Learning Workflow for Improved Hybrid Pharmacometric Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Model‐informed precision dosing is often constrained by the limited generalizability of traditional population pharmacokinetic models, especially in critically ill patients. A hybrid machine learning‐population pharmacokinetic framework is proposed to improve a priori pharmacokinetic predictions by integrating real‐world clinical data.
Freek J. A. Relouw, Jort J. M. T. Lokers, Tim Preijers, Sebastiaan D. T. Sassen, Natal A. W. van Riel, Birgit C. P. Koch   +5 more
wiley   +1 more source

Efficacy and safety of an intravenous amikacin-containing regimen as initial therapy in <i>Mycobacterium avium</i> complex pulmonary disease. [PDF]

J Clin Tuberc Other Mycobact Dis
Teramoto T, Ito A, Nakanishi Y, Hashimoto T, Ishida T.   +4 more
europepmc   +1 more source

Relevance‐Based Score for MIPD Model Selection: Systematic Review and External Evaluation of popPK Tacrolimus Models in Adult Transplant Recipients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Selecting the most relevant models for model‐informed precision dosing (MIPD) remains challenging, particularly when numerous population pharmacokinetic (popPK) models are available, making external evaluation of all candidates time‐ and resource‐consuming.
Samuel Baroudi, Bénédicte Franck, Jean‐Baptiste Woillard, Ntobe‐Bunkete Béni, Emmanuelle Comets, Florian Lemaitre   +5 more
wiley   +1 more source