Results 181 to 190 of about 22,324 (258)

Early Prediction of Outcome Using Lactate Dehydrogenase and Amplitude‐Integrated EEG in Transported Newborn Infants with Hypoxic–Ischaemic Encephalopathy

open access: yesActa Paediatrica, Volume 115, Issue 8, Page 1746-1754, August 2026.
ABSTRACT Aim To investigate whether early lactate dehydrogenase (LDH) and amplitude‐integrated electroencephalography (aEEG) improve the prediction of outcome in outborn infants transported for therapeutic hypothermia. Method Secondary analysis of a randomised controlled trial (2016–2019) including 113 asphyxiated newborn infants randomised to ...
Hang T. T. Tran   +5 more
wiley   +1 more source

Planning Intermittent CalciNeurin Inhibitor Controls—The piCNIc Retrospective Cohort Study

open access: yesClinical Transplantation, Volume 40, Issue 8, August 2026.
ABSTRACT Background Calcineurin inhibitors (CNIs) are essential in immunosuppressive therapy after solid organ transplantation (SOT). Their narrow therapeutic index and inter‐ and intra‐individual variability require therapeutic drug monitoring (TDM), but optimal monitoring frequency remains unclear.
Veronica Bellissimo   +9 more
wiley   +1 more source

Oral Stepdown Therapy for Gram‐Negative Bloodstream Infections: A Systematic Review and Meta‐Analysis

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Forest plots of mortality, clinical failure and microbiological failure in patients receiving oral stepdown or continuing intravenous treatment for Gram‐negative bloodstream infections. ABSTRACT Background Early oral step‐down has been proposed as a strategy to optimize antimicrobial use in Gram‐negative bloodstream infections (BSIs).
Lorenzo Onorato   +5 more
wiley   +1 more source

Geographical variability in dabigatran dosing within New Zealand

open access: yesInternal Medicine Journal, Volume 56, Issue 8, Page 1433-1437, August 2026.
Abstract Dabigatran etexilate is an oral anticoagulant with increased risk of bleeding at high drug exposure. It is available in three capsule strengths (75, 110 and 150 mg). We analysed New Zealand dispensing data from 2019 to 2023 to compare use between health districts. Overall use was similar across districts.
Liam T. Berryman   +4 more
wiley   +1 more source

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