Results 191 to 200 of about 114,153 (288)

TDM. From the standpoint of clinicians. 2. TDM of antiepileptics or lithium.

open access: yesRinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 1988
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, Volume 16, Issue 10, Page 1847-1856, October 2026.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, Volume 78, Issue 10, Page 1424-1437, October 2026.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Intelligent Distributed Optical Fiber Sensing in Transportation Infrastructures: Research Progress, Applications, and Challenges

open access: yesAdvanced Photonics Research, Volume 7, Issue 10, October 2026.
Distributed optical fiber sensing (DOFS) is reviewed as a transformative technology for intelligent monitoring of transportation infrastructures. Advances in sensing fibers, cable design, and data analytics are summarized alongside representative field applications.
Xin Gui   +11 more
wiley   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3375-3386, October 2026.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen   +14 more
wiley   +1 more source

Next-generation hybrid bioanalytical platforms and clinical integration of TDM technologies for precision monitoring to optimize last-resort antibiotic therapy. [PDF]

open access: yesFront Pharmacol
Inamdar A   +10 more
europepmc   +1 more source

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