Results 231 to 240 of about 3,587,529 (301)

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Teacher-Identified Priorities and Resource Use in Government-Supported School Food and Nutrition Education in Korea. [PDF]

Nutrients
Lee SJ, Oh J, Lee KW.
europepmc   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

Task Graph Generation for Heterogeneous UAV Swarms in Partially Observable Adversarial Environments. [PDF]

Entropy (Basel)
Li W, Feng Y.
europepmc   +1 more source

The dual roles of social support and coping in music performance anxiety: a systematic review of evidence from music students and professional musicians. [PDF]

Front Psychol
Wang Y, Lan Y.
europepmc   +1 more source

Motivational climate in school sport and adolescent mental health: a systematic review. [PDF]

Front Psychiatry
Wei Y, Lai GN, Ji C, Yang XM, Tie CY.
europepmc   +1 more source

"….it is like a single body being controlled by two heads.": exploring cognitive, social, and affective engagement in L2 collaborative writing. [PDF]

Front Psychol
Kaya F.
europepmc   +1 more source

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The Memorable Teacher: Implications for Teacher Selection

The Journal of Negro Education, 1986
The problem of identifying people who are likely to become good elementary and secondary school teachers is continually wrestled with by educational researchers involved in the study of teaching and schooling, by colleges and universities that prepare teachers, by state education agencies that set qualification and monitoring standards, and by local ...
Sylvia T. Johnson, Sukai Prom-Jackson
openaire   +1 more source

Selecting successful teachers: The predictive validity of the urban teacher selection interview

The Teacher Educator, 1996
Abstract The Urban Teacher Selection Interview (UTSI) was designed by Martin Haberman to differentiate between students who will become successful teachers and those who will not be successful. The purpose of this study was to assess the predictive validity of the UTSI for three different groups of teacher candidates (traditional, alternative licensure,
Maryan K. Baskin, Steven M. Ross, Dennie L. Smith   +2 more
openaire   +1 more source