Results 31 to 40 of about 2,119,946 (290)

The Turbulent Sixties at Rutgers: An Interview with Richard P. McCormick

open access: yes, 1997
Richard P. McCormick’s professional life has been so intertwined with Rutgers University’s history that it is difficult to imagine anyone who knows more about Rutgers or who has put a greater imprint on the institution.
Birkner, Michael J.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A Hypermedia-Supported program and its effect on developing historical reasoning skills among first year secondary school students [PDF]

open access: yesInternational Journal of Instructional Technology and Educational Studies
This study investigated the effect of a hypermedia-supported program on developing historical reasoning skills among first-year secondary school students in Egypt.
kholoud ibrahem, Samia Fayed
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

German Question in 1945–1949: Research of the Problem in Anglo-American Historiography

open access: yesHistoria i Polityka, 2018
The article is devoted to the research of the main streams in Anglo-American historiography concerning German problem in 1945–1949. Two main directions in Anglo-American historical science are identified and characterized.
Iryna Kaviaka
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

ATATÜRK İLKELERİ ve İNKILÂP TARİHİ DERSİNİN UZAKTAN EĞİTİM ŞEKLİNDE VERİLMESİNİN ÖĞRENCİ GÖRÜŞLERİ AÇISINDAN DEĞERLENDİRİLMESİ

open access: yesTurkish History Education Journal, 2017
Bu araştırmanın amacı, Atatürk İlkeleri ve İnkılâp Tarihi dersini uzaktan eğitim olarak alan öğrencilerin bu dersin uzaktan eğitim şeklinde veriliyor olmasına ilişkin görüşlerini tespit etmektir. Araştırmada veri toplama aracı olarak kullanılan anketler,
Sezai ÖZTAŞ, Bülent KILIÇ
doaj   +1 more source

Teaching History to Petersburg Gymnasium Students in the First Half of the 19th Century

open access: yesВопросы образования, 2021
This article explores the practices of teaching history in men’s gymnasiums of the first half of the 19th century in Petersburg, analyzing the curricula, the content of textbooks, and examinations as well as theoretical developments and methodological ...
Tatiana Pashkova
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Los jóvenes y la Historia en el Mercosur. Temporalidades y enseñanza de la Historia

open access: yesClio y Asociados, 2017
In this work we present a quantitative research that investigates the concepts of time more accepted among students. Data analyzed the Argentinian answers to the questionnaire of project ‘Youth and history in MERCOSUR’.
Juliano Mainardes Waiga
doaj   +1 more source

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