Results 1 to 10 of about 36,732 (311)

Evaluating the technetium-99 m pertechnetate flow protocol for Graves’ disease: methodological insights: a case series [PDF]

open access: yesJournal of Medical Case Reports
Background Graves’ disease is the most prevalent cause of hyperthyroidism globally, with technetium-99m pertechnetate widely utilized in its diagnosis.
Jaber Abdulwahab Asiri   +10 more
doaj   +2 more sources

Extracting Technetium from Neutral Molybdenum Solution with Activated Carbon Filber

open access: yesJournal of Isotopes, 2021
The use of the chromatographic method to extract 99Tcm from the low specific activity 99Mo solution is an effective way to obtain medical isotope 99Tcm that meeting clinical requirements.
SONG Zhihao;ZHANG Yunhan;WANG Ning;GUO Hongli;ZHAO Hailong;GAO Xiang
doaj   +1 more source

The Chemistry of Phenylimidotechnetium(V) Complexes with Isocyanides: Steric and Electronic Factors

open access: yesMolecules, 2022
Organometallic approaches are of ongoing interest for the development of novel functional 99mTc radiopharmaceuticals, while the basic organotechnetium chemistry seems frequently to be little explored. Thus, structural and reactivity studies with the long-
Guilhem Claude   +5 more
doaj   +1 more source

Synthesis and Structure of Oxygen Deficient Lead-Technetium Pyrochlore, the First Example of a Valence V Technetium Oxide

open access: yesFrontiers in Chemistry, 2021
The structure of lead-technetium pyrochlore has been refined in space group Fd3¯m with a = 10.36584(2) Å using a combination of synchrotron X-ray and neutron powder diffraction data and confirmed via Electron Diffraction.
Brendan J. Kennedy   +13 more
doaj   +1 more source

Historical efforts to develop 99mTc-based amyloid plaque targeting radiotracers

open access: yesFrontiers in Nuclear Medicine, 2022
Imaging biomarkers have changed the way we study Alzheimer's disease and related dementias, develop new therapeutics to treat the disease, and stratify patient populations in clinical trials.
Ghazaleh Takalloobanafshi   +5 more
doaj   +1 more source

Can Sentinel Lymph Node Biopsy Predict Various Levels of Echelon Nodes in Oral Cancers?

open access: yesInternational Archives of Otorhinolaryngology, 2020
Introduction The efficacy of sentinel node biopsy in early stage oral cancer is well established. Its evolving role can be reinforced by further studies.
Ramya Rathod   +5 more
doaj   +1 more source

New Bioconjugated Technetium and Rhenium Folates Synthesized by Transmetallation Reaction with Zinc Derivatives

open access: yesMolecules, 2021
The zinc dithiocarbamates functionalized with folic acid 2Zn and 3Zn were synthesized with a simple straightforward method, using an appropriated folic acid derivative and a functionalized zinc dithiocarbamate (1Zn).
Jordi Borràs   +6 more
doaj   +1 more source

New leads for fragment-based design of rhenium/technetium radiopharmaceutical agents

open access: yesIUCrJ, 2017
Multiple possibilities for the coordination of fac-[Re(CO)3(H2O)3]+ to a protein have been determined and include binding to Asp, Glu, Arg and His amino-acid residues as well as to the C-terminal carboxylate in the vicinity of Leu and Pro.
Alice Brink, John R. Helliwell
doaj   +1 more source

Trends in coordination of rhenium organometallic complexes in the Protein Data Bank

open access: yesIUCrJ, 2022
Radiopharmaceutical development has similar overall characteristics to any biomedical drug development requiring a compound's stability, aqueous solubility and selectivity to a specific disease site. However, organometallic complexes containing 188/186Re
Alice Brink   +2 more
doaj   +1 more source

Biodistribution Study of the Anaesthetic Sodium Phenobarbital Labelled with Technetium-99m in Swiss Mice Infected with Schistosoma mansoni Sambon, 1907

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
Technetium-99m (99mTc) is a radionuclide that has negligible enviromnental impact, is easily available, inexpensive and can be used as a radioactive tracer in biological experiences.
Susana Balmant Emerique Simões   +5 more
doaj   +1 more source

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