Results 1 to 10 of about 62,440 (290)

Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)

open access: yesJournal of Medicinal Chemistry, 2023
Technetium-99m is the workhorse of diagnostic nuclear medicine. The aim of the work is to analyze the technetium-99m patents since 2000 to photograph its innovation. QUESTEL’s ORBIT Intelligence system was used for the collection of technetium inventions
M. Riondato   +6 more
semanticscholar   +1 more source

Role of Pure Technetium Chemistry: Are There Still Links to Applications in Imaging?

open access: yesInorganic Chemistry, 2023
The discovery and development of new 99mTc-based radiopharmaceuticals or labeled drugs in general is based on innovative, pure chemistry and subsequent, application-targeted research. This was the case for all currently clinically applied imaging agents.
R. Alberto
semanticscholar   +1 more source

Efficient 1-Hour Technetium-99 m Pyrophosphate Imaging Protocol for the Diagnosis of Transthyretin Cardiac Amyloidosis

open access: yesCirculation Cardiovascular Imaging, 2020
Background: Technetium-99 m pyrophosphate protocols for transthyretin cardiac amyloidosis diagnosis have variably used 1- and 3-hour imaging time points.
A. Masri   +9 more
semanticscholar   +1 more source

Spontaneous redox continuum reveals sequestered technetium clusters and retarded mineral transformation of iron

open access: yesCommunications Chemistry, 2020
The sequestration of metal ions into the crystal structure of minerals is common in nature. To date, the incorporation of technetium(IV) into iron minerals has been studied predominantly for systems under carefully controlled anaerobic conditions ...
D. Boglaienko   +11 more
semanticscholar   +1 more source

The Shortage of Technetium-99m and Possible Solutions

open access: yes, 2020
Following a major shortage of 99Mo in the 2009–2010 period, concern grew that the aging reactor production facilities needed to be replaced.
T. Ruth
semanticscholar   +1 more source

Modeling and Speciation Study of Uranium(VI) and Technetium(VII) with TBP

open access: yes, 2020
Among the fission products present in the spent nuclear fuel, technetium exhibits a singular behavior in reprocessing operations performed by solvent extraction. Indeed, this strong acid readily dissociates to form the oxo-anion TcO4 − that may interfere
P. Moeyaert   +7 more
semanticscholar   +1 more source

Dramaturgy of technetium nanoparticles delivery process in human gum cancer cells, tissues and tumors treatment under synchrotron radiation

open access: yesDental, Oral and Maxillofacial Research, 2019
In the current study, thermoplasmonic characteristics of Technetium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of ...
A. Heidari   +3 more
semanticscholar   +1 more source

Solitary Parathyroid Adenoma Localization in Technetium Tc99m Sestamibi SPECT and Multiphase Multidetector 4D CT

open access: yesAmerican Journal of Neuroradiology, 2018
BACKGROUND AND PURPOSE: Minimally invasive parathyroid surgery relies critically on image guidance, but data comparing the efficacy of various imaging modalities are scarce.
T. Vu   +10 more
semanticscholar   +1 more source

Technetium Complexes and Radiopharmaceuticals with Scorpionate Ligands

open access: yesMolecules, 2018
Scorpionate ligands have played a crucial role in the development of technetium chemistry and, recently, they have also fueled important advancements in the discovery of novel diagnostic imaging agents based on the γ-emitting radionuclide technetium-99m.
P. Martini   +5 more
semanticscholar   +1 more source

Behavior of technetium in nuclear waste vitrification processes

open access: yesJournal of Radioanalytical and Nuclear Chemistry, 2015
Nearly 100 tests were performed with prototypical melters and off-gas system components to investigate the extents to which technetium is incorporated into the glass melt, partitioned to the off-gas stream, and captured by the off-gas treatment system ...
I. Pegg
semanticscholar   +1 more source

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