Results 21 to 30 of about 33,555 (260)

Synthesis and Evaluation of ^99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

Pharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan, Yitong Liu, Lihao Liao, Jinyu Hao, Yuhao Jiang, Jianyong Jiang, Junbo Zhang   +6 more
doaj   +1 more source

False‑positive technetium‑99m methylene diphosphonate bone scan activity in the orbit in a patient with a history of breast carcinoma [PDF]

, 2018
Metastasis of breast carcinoma to the orbit is an uncommon entity and carries a poor prognosis. This case report presents false-positive technetium-99m methylene diphosphonate activity in the right orbit of a patient with a history of a primary breast ...
Bonnet, Sarah E., Palko, Joel R.
core   +2 more sources

Technetium Complexes and Radiopharmaceuticals with Scorpionate Ligands

Molecules, 2018
Scorpionate ligands have played a crucial role in the development of technetium chemistry and, recently, they have also fueled important advancements in the discovery of novel diagnostic imaging agents based on the γ-emitting radionuclide ...
Petra Martini, Micol Pasquali, Alessandra Boschi, Licia Uccelli, Melchiore Giganti, Adriano Duatti   +5 more
doaj   +1 more source

The optimization method for synthesis of technetium-99m-luteolin as radiotracer in the development of cancer drugs from flavonoid

Journal of Advanced Pharmaceutical Technology & Research, 2020
The aim of this study is to find the optimum conditions of labeling luteolin flavonoid compounds with technetium-99m (99mTc) to meet the purity requirements stated in the United States Pharmacopeia. This compound is expected to be a potential radiotracer
Danni Ramdhani, Maula Eka Sriyani, S Fairuz Nabila   +2 more
doaj   +1 more source

Effect of an extract of Centella asiatica on the biodistribution of sodium pertechnetate (Na^99mTcO₄) and on the fixation of radioactivity on blood constituents [PDF]

, 2008
This study evaluates the effects of an acute treatment with a Centella asiatica (CA) extract on the biodistribution of the radiopharmaceutical Na99mTcO4 and on the fixation of technetium-99m on blood constituents. Wistar rats were treated with CA extract
Adenilson de Souza da Fonseca, Benarroz M. O., Bernardo-Filho M., Capriles P. V., Claudia Leite Diniz, Danielle Santos de Almeida, Fernanda Santos do Carmo, Fonseca A. S., Frydman J. N. G., Goel H. C., Inamdar P. K., Jayashree G., Mario Bernardo Filho, Moreno S.R., Owunwanne A., Padma P. R., Rebello B. M., Saha G. B., Sebastião David Santos-Filho, Sharma J., Shobi V., Simões C. M. O., Sotiris Missailidis   +22 more
core   +4 more sources

Reverse cardiac remodelling and dysfunction in A97S transthyretin cardiac amyloidosis after tafamidis treatment

ESC Heart Failure, 2022
Transthyretin cardiomyopathy (ATTR‐CM) is an under‐recognized cause of heart failure, but it has received increasing attention due to the availability of treatment options.
Yuan‐Kun (Aden) Wu, Cheng‐Hsuan Tsai, Mao‐Yuan Su, Chi‐Chao Chao, Mei‐Fang Cheng, Chia‐Tung Shun, Sung‐Tsang Hsieh, Yen‐Hung Lin   +7 more
doaj   +1 more source

Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]

, 2003
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Brinkbäumer, K., Hahn, K., Keßler, M., Linke, R., Sommer, H., Tiling, R., Untch, M.   +6 more
core   +1 more source

Comparison of the absorbed dose for 99m Tc-diethylenetriaminepentaacetic acid and 99m Tc-ethylenedicysteine radiopharmaceuticals using medical internal radiation dosimetry

Journal of Medical Signals and Sensors, 2015
The aim of this study was the investigation of absorbed dose to the kidneys, spleen, and liver during technetium-99 m ethylene dicysteine and technetium-99 m diethylenetriaminepentaacetic acid ( 99m Tc-EC and 99m Tc-DTPA) kidney scan.
Shokufeh Pirdamooie, Ahmad Shanei, Masoud Moslehi   +2 more
doaj   +1 more source

Radiolabeling of cidofovir with technetium-99m and biodistribution studies

Brazilian Journal of Pharmaceutical Sciences, 2020
Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that enables real-time monitoring of the drug. Essays were performed in vitro, showing high radiolabel stability within 24 h. Blood clearance, biodistribution studies, and
Raquel Gregorio Arribada, Nara Caroline Pereira, Valbert Nascimento Cardoso, Armando da Silva Cunha Júnior, André Luís Branco de Barros   +4 more
doaj   +1 more source

DETERMINATION OF NORMAL THYROID TECHNETIUM-99M UPTAKE VALUE IN A SINGLE CENTRE PAKISTANI POPULATION

Pakistan Armed Forces Medical Journal, 2021
Objective: To determine the normal value of thyroid Technetium-99m uptake value in a single centre Pakistani population. Study Design: Cross-sectional study.
Asad Malik, Fida Hussain, Muhammad Ashraf, Saima Seher, Ali Jamal, Shahzad Akbar   +5 more
doaj   +1 more source