Results 21 to 30 of about 22,718 (165)

A Review of Advances in Molecular Imaging of Rheumatoid Arthritis: From In Vitro to Clinic Applications Using Radiolabeled Targeting Vectors with Technetium-99m [PDF]

Life (Basel)
Ali M, Benfante V, Di Raimondo D, Laudicella R, Tuttolomondo A, Comelli A.   +5 more
europepmc   +3 more sources

A Picture of Modern Tc-99m Radiopharmaceuticals: Production, Chemistry, and Applications in Molecular Imaging

Applied Sciences, 2019
Even today, techentium-99m represents the radionuclide of choice for diagnostic radio-imaging applications. Its peculiar physical and chemical properties make it particularly suitable for medical imaging.
Alessandra Boschi, Licia Uccelli, Petra Martini   +2 more
doaj   +1 more source

Technetium Complexes and Radiopharmaceuticals with Scorpionate Ligands

Molecules, 2018
Scorpionate ligands have played a crucial role in the development of technetium chemistry and, recently, they have also fueled important advancements in the discovery of novel diagnostic imaging agents based on the γ-emitting radionuclide ...
Petra Martini, Micol Pasquali, Alessandra Boschi, Licia Uccelli, Melchiore Giganti, Adriano Duatti   +5 more
doaj   +1 more source

The optimization method for synthesis of technetium-99m-luteolin as radiotracer in the development of cancer drugs from flavonoid

Journal of Advanced Pharmaceutical Technology & Research, 2020
The aim of this study is to find the optimum conditions of labeling luteolin flavonoid compounds with technetium-99m (99mTc) to meet the purity requirements stated in the United States Pharmacopeia. This compound is expected to be a potential radiotracer
Danni Ramdhani, Maula Eka Sriyani, S Fairuz Nabila   +2 more
doaj   +1 more source

Synthesis and Evaluation of ^99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

Pharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan, Yitong Liu, Lihao Liao, Jinyu Hao, Yuhao Jiang, Jianyong Jiang, Junbo Zhang   +6 more
doaj   +1 more source

Comparison of the absorbed dose for 99m Tc-diethylenetriaminepentaacetic acid and 99m Tc-ethylenedicysteine radiopharmaceuticals using medical internal radiation dosimetry

Journal of Medical Signals and Sensors, 2015
The aim of this study was the investigation of absorbed dose to the kidneys, spleen, and liver during technetium-99 m ethylene dicysteine and technetium-99 m diethylenetriaminepentaacetic acid ( 99m Tc-EC and 99m Tc-DTPA) kidney scan.
Shokufeh Pirdamooie, Ahmad Shanei, Masoud Moslehi   +2 more
doaj   +1 more source

99m-Technetium galactosyl human serum albumin scanning to evaluate liver function after stereotactic body radiotherapy for hepatocellular carcinoma: A case report

Radiology Case Reports, 2019
The primary choice among treatment options for liver malignancies is surgery. However, if surgery cannot be performed, Stereotactic body radiotherapy (SBRT) may be effective.
Osamu Tanaka, MD, Kazutaka Miki, RT, Takuya Taniguchi, MP, Takao Kojima, MD, Akihiro Ohbora, MD, Chiyoko Makita, MD, Masayuki Matsuo, MD   +6 more
doaj   +1 more source

Reverse cardiac remodelling and dysfunction in A97S transthyretin cardiac amyloidosis after tafamidis treatment

ESC Heart Failure, 2022
Transthyretin cardiomyopathy (ATTR‐CM) is an under‐recognized cause of heart failure, but it has received increasing attention due to the availability of treatment options.
Yuan‐Kun (Aden) Wu, Cheng‐Hsuan Tsai, Mao‐Yuan Su, Chi‐Chao Chao, Mei‐Fang Cheng, Chia‐Tung Shun, Sung‐Tsang Hsieh, Yen‐Hung Lin   +7 more
doaj   +1 more source

Technetium-99m nitrido radiopharmaceuticals with unprecedented biological properties

Brazilian Archives of Biology and Technology, 2002
The chemical methods for the production of technetium-99m radiopharmaceuticals containing a terminal TcºN triple bond have been established more than a decade ago.
Adriano Duatti, Alessandra Boschi, Licia Uccelli   +2 more
doaj   +1 more source

Radiolabeling of cidofovir with technetium-99m and biodistribution studies

Brazilian Journal of Pharmaceutical Sciences, 2020
Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that enables real-time monitoring of the drug. Essays were performed in vitro, showing high radiolabel stability within 24 h. Blood clearance, biodistribution studies, and
Raquel Gregorio Arribada, Nara Caroline Pereira, Valbert Nascimento Cardoso, Armando da Silva Cunha Júnior, André Luís Branco de Barros   +4 more
doaj   +1 more source