Results 121 to 130 of about 9,393,805 (363)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Baldo Stančić, PhD in Technical Sciences

open access: yesKartografija i Geoinformacije, 2013
Baldo Stančić defended his doctoral thesis Modeling Archival Space-Time Cadastral Data in the Modern Technological Environment at theUniversity ofZagreb, Faculty of Geodesy onFebruary 11, 2013. The Committee for Defense consisted of Prof. Dr.
Miodrag Roić
doaj  

Organization and Standardization of Police Science Technics

open access: yesJournal of Criminal Law and Criminology (1931-1951), 1949
Ralph F. Turner is an Assistant Professor of Police Administration at Michigan State College and previous to this appointment was Superintendent of the Kansas City (Missouri) Police Laboratory. As a qualified forensic scientist he can appreciate the problems confronting workers in this field of criminal investigation.
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Blaženka Mičević, PhD in Technical Sciences

open access: yesKartografija i Geoinformacije, 2016
Blaženka Mičević defended her doctoral dissertation titled Development of Agricultural Land Administration System within the Agricultural Policy Context of the Republic of Croatia at the Faculty of Geodesy, University in Zagreb on May 6, May 2016.
Siniša Mastelić Ivić
doaj  

On the Possible Transformation and Vanishment of Epistemic Objects [PDF]

open access: yes, 2016
When considering the question of possible transformation and disappearance of scientific objects, it is useful to distinguish between epistemic and technical objects. This paper presents preliminary observations and offers a typology of obsolescence.
Rheinberger, Hans-Jörg
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Facilities for meteorological research at NASA Goddard/Wallops Flight Facility [PDF]

open access: yes
The technical characteristics of the Atmospheric Sciences Research Facility, the improvements being made to the instrumentation there which will enhance its usefulness in atmospheric research, and several of the on-going research programs are described ...
Carr, R. E., Gerlach, J. C.
core   +1 more source

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