Results 41 to 50 of about 2,275,255 (233)

IMPROVEMENT OF FINANCIAL SUPPORT OF RAISING PRODUCT QUALITY WITH THE HELP OF SMART MANAGEMENT INFORMATION SYSTEMS [PDF]

open access: yesProceedings on Engineering Sciences
We analysed the directions for improving financing for the growth of quality in the conditions of smart production and revealed the advantages and features of their realisation in developing and developed countries.
Sultonali U. Mekhmonov   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

“Technologies of the law/ law as a technology” [PDF]

open access: yesHistory of Science, 2018
Historians of science and technology and STS practitioners have always taken intellectual property very seriously but, with some notable exceptions, they have typically refrained from looking “into” it. There is mounting evidence, however, that they can open up the black box of IP as effectively as they have done for the technosciences, enriching their
Mario Biagioli, Marius Buning
openaire   +4 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Evaluation of Extension Agents Commitment to the Agricultural Loans and Inputs Supply Programme on Special Rice Production in Delta State, Nigeria

open access: yesJournal of Applied Sciences and Environmental Management, 2014
The study evaluated the activities of Extension agents on Agricultural Loans and Inputs Supply Programme participant farmers’ rice output/income. Data were collected with the aid of questionnaire from 60 Extension agents (participating in the ALIS ...
G F Okwuokenye, D U Okoedo-Okojie
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

TECHNOLOGY, ANALYSIS, AND STUDY DEVELOPMENT OF HEPATOPROTEC-TIVE ACTION OF SUPPOSITORIES WITH RIBOXINUM

open access: yesФармация и фармакология (Пятигорск), 2015
То elaborate the composition of the suppositories with riboxiniirn we have studied physical and chemical, and structural and mechanical characteristics of different bases. Witepsol-H15 was chosen as a preferable base.
O. V. Michnik   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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