Results 71 to 80 of about 7,527,785 (272)
Modern possibilities of treating brain tumors: intraoperative technologies in neurooncology
Клиническая практикаThe fundamental principle of neurooncology is the maximal removal of the tumor, simultaneously minimizing the effects on the healthy brain structures.
Arthur I. Nafikov +12 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
SeparationsWith the rapid economic development and the continuous growth in the demand for new energy vehicles and energy storage systems, a significant number of waste lithium-ion batteries are expected to enter the market in the future.
Shuwen Wang +8 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
LandThere are few studies on the representation of older people regarding aids and assistive devices and even fewer that incorporate more inclusive views (gender, emotions, anti-ageist, territorial or land approach) as well as virtual or land ethnography or ...
Vanessa Zorrilla-Muñoz +3 more
doaj +1 more source
Innovative technologies for industrial wastes [PDF]
, 2003 This article is intended to provide several case studies of successful waste management of a few selected industries in their attempts to become “environmental-conscious” firms.
Chik, Abdul Razak, Jusoh, Juzhar
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The use of advanced e-technologies in state governance
Вестник Российского экономического университета имени Г. В. Плеханова, 2019 Local, state and federal bodies of power use e-technologies (from automation to artificial intellect) in order to improve the life of the population. The new generation of computer complexes excel people in the intellect quality as a strategic tool of ...
L. N. Alekseeva
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source