Results 81 to 90 of about 7,420,775 (255)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The use of advanced e-technologies in state governance
Вестник Российского экономического университета имени Г. В. Плеханова, 2019 Local, state and federal bodies of power use e-technologies (from automation to artificial intellect) in order to improve the life of the population. The new generation of computer complexes excel people in the intellect quality as a strategic tool of ...
L. N. Alekseeva
doaj +1 more source
Learning&Information Technologies Cartography [PDF]
, 2012 Nowadays, many researches focus their efforts in studies and applications on the Learning area. However, there is a lack of a reference system that permits to know the positioning and the existing links between Learning and Information Technologies. This
Flores Naranjo, Pamela Catherine +1 more
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Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Healthcare technologies and professional vision [PDF]
, 2003 This paper presents some details from an observational evaluation of a computer assisted detection tool in mammography. The use of the tool, its strengths and weaknesses, are documented and its impact on reader's 'professional vision' (Goodwin 1994 ...
Hartswood, Mark +5 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Development of Media Literacy as a Key Requirement of the European Union
Проблеми на постмодерността, 2019 This article traces the key documents of the European Union related to the media literacy development. Along with that it offers a new and more extended understanding of the very concept due to the rapid dynamics of the interaction of various political ...
Danail Danov
doaj
A special place into assistive technologies is taken up by the speech recognition and speech synthesizer, which can be used by many different users, persons with visual, language or mobility disabilities.
Ion SMEUREANU, Narcisa ISAILA
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