Results 21 to 30 of about 195 (189)

The Use of Immersive Technologies for Design Reviews

, 2020
Analysing and manipulating 3D objects are key competences for product designers. Although there is a substantial amount of research on review tools based on immersive technologies related to industrial practices, a comparison with traditional design reviews on an educational level is less prominent in scientific literature.
Sander Van Goethem, Jouke Verlinden, Ian Garcia, Rune Degryse, Siebe Perdieus, Regan Watts, Stijn Verwulgen   +6 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The Use of Immersive Technologies for Concept Design

, 2020
In this paper, a method is proposed for using virtual reality for concept design with the Gravity Sketch VR application and a virtual reality headset. The method for augmented concept design is then tested against traditional sketching on paper. The participants were thirteen product development master students, challenged to design backpacks in VR and
Sander Van Goethem, Regan Watts, Arno Dethoor, Rik Van Boxem, Kaz van Zegveld, Jouke Verlinden, Stijn Verwulgen   +6 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A pilot study to evaluate the usability of an immersive virtual reality application for medical training in acute appendicitis.

Revista Española de Educación Médica
Introduction: Virtual reality (VR) is transforming medical education through didactic and interactive simulations of clinical cases. Immersive virtual reality (IVR) allows users to experience full immersion, creating the perception of being inside the ...
Iñigo Alzaga, Verónica Tíscar González, Igor Alberdi San Román, Ane Arcaraz Arnaiz, Alberto Loizate Totaricaguena, Asier Legarreta Gaminde, Itsaso Villanueva Ibero, Edorta Ander Pérez García   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Innover pour mieux chercher : l’impact des TICEs et du numérique sur la recherche scientifique en sciences humaines

Mediterranean Migration & Medias, Revue des Humanités
Les technologies numériques ont profondément modifié la manière de mener la recherche en sciences humaines, notamment dans les domaines de la littérature et des arts.
Imane ABOUD
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source