Results 101 to 110 of about 1,594,829 (307)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

An Analysis of the Influence of Students´ Technological Culture on Their Technology

open access: yes, 2011
decade has raised the interest among the research community on the acceptance and use of these systems by both teachers and students. At first, the implementation of LMS was based on their technical design and the adaptation of the learning processes ...
Dueñas Rugnon, Oscar Lorenzo   +3 more
core  

Effect of user experience on technology acceptance: the case of foss [PDF]

open access: yes, 2009
Free and open source software (FOSS) movement essentially arises like answer to the evolution occurred in the market from the software, characterized by the closing of the source code.
Bueno Ávila, Salvador   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Evaluation Virtual Assistant Chatbot Acceptance with an Unified Technology Acceptance and Use of Technology-Based Model

open access: yesJournal of Information Systems and Informatics
The virtual assistant chatbot in the MyTelkomsel application is a company's effort to achieve goals and improve business performance. Chatbot as a virtual assistant has advantages and disadvantages.
Radhiya Sabila   +2 more
doaj   +1 more source

Values in Water [PDF]

open access: yes, 2018
Inaugural speech spoken in acceptance of the chair ‘Ethics of water engineering’ at the Faculty of Technology, Policy and Management of Delft University of Technology on 16 November ...
Doorn, Neelke
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

A structural model of technology acceptance

open access: yesSA Journal of Industrial Psychology, 2015
Orientation: Enterprise resource systems have not always led to significant organisational enhancement and many projects in which these systems have been implemented turn out to be over budget, not on time and unsuccessful.
Etienne Erasmus   +2 more
doaj   +1 more source

Business-to-consumer e-commerce in Nigeria: Prospects and challenges [PDF]

open access: yes, 2011
The growth of Internet usage in Nigeria continues to increase, recording over 90% growth rate between 2000 and 2008. While businesses in Nigeria are reported to have online access with opportunity for ecommercial activities, customers in the country ...
Adewoye, J. O.   +2 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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