Results 31 to 40 of about 247,520 (248)

Evaluating a University-Wide Digital Skills Programme: Understanding the Student Journey

Education Sciences
Digital competencies are critical to success in higher education, and yet these skills are often not explicitly taught to students. We have previously designed and evaluated a university-wide digital skills programme using quantitative methods.
Nabila A. S. Raji, Eleanor J. Dommett
doaj   +1 more source

Weaknesses of ICT integration in the initial teacher education curriculum

Computers and Education Open, 2023
The article presents a Portuguese national study on integrating information and communication technologies (ICT) in initial teacher education courses (ITE), which sought to highlight to what extent ICT are presently considered in the training curriculum ...
Cristiano Rogério Vieira, Neuza Pedro
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Dataset on student experiences and perceptions of Emergency Remote Teaching (ERT) in an Irish University

Data in Brief, 2022
This paper presents a dataset from a survey of student experiences and perceptions of Emergency Remote Teaching (ERT) during the COVID-19 pandemic in the Munster Technological University, a new higher education institute in the south-west of Ireland ...
Gearóid Ó. Súilleabháin, Tom Farrelly, Sean Lacey   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Digital Teaching and Digital Medicine: A national initiative is needed

GMS Journal for Medical Education, 2018
The advancing digitization of the healthcare system requires that in the future digital skills should be communicated to students much more. In addition, digital teaching and learning technologies should be used wherever they offer real benefits over ...
Haag, Martin, Igel, Christoph, Fischer, Martin R., German Medical Education Society (GMA), Committee “Digitization – Technology-Assisted Learning and Teaching”, Joint working group “Technology-enhanced Teaching and Learning in Medicine (TeLL)” of the German Association for Medical Informatics, Biometry and Epidemiology (gmds) and the German Informatics Society (GI)   +4 more
doaj   +1 more source

Content-specific differences in Padlet perception for collaborative learning amongst undergraduate students

Research in Learning Technology, 2021
Collaborative learning offers benefits but there is insufficient information on how students perceive specific digital tools supporting collaborative learning and whether there are content-related differences in students’ perceptions.
Kosha J. Mehta, Isabelle Miletich, Michael Detyna   +2 more
doaj   +1 more source